Karyopharm Therapeutics Inc

NASDAQ:KPTI USA Biotechnology
Market Cap
$153.81 Million
Market Cap Rank
#17199 Global
#6536 in USA
Share Price
$8.40
Change (1 day)
+0.24%
52-Week Range
$3.54 - $10.09
All Time High
$27.72
About

Karyopharm Therapeutics Inc., a commercial-stage pharmaceutical company, discovers, develops, and commercializes drugs directed against nuclear export for the treatment of cancer and other diseases in the United States. The company discovers, develops, and commercializes novel and small molecule Selective Inhibitor of Nuclear Export (SINE) compounds that inhibit the nuclear export protein exporti… Read more

Market Cap & Net Worth: Karyopharm Therapeutics Inc (KPTI)

Karyopharm Therapeutics Inc (NASDAQ:KPTI) has a market capitalization of $153.81 Million ($153.81 Million) as of March 19, 2026. Listed on the NASDAQ stock exchange, this USA-based company holds position #17199 globally and #6536 in its home market, demonstrating a 2.07% increase in market value over the past year.

Market capitalization, also known as net worth in stock markets, is calculated by multiplying Karyopharm Therapeutics Inc's stock price $8.40 by its total outstanding shares 18311000 (18.31 Million).

Karyopharm Therapeutics Inc Market Cap History: 2015 to 2026

Karyopharm Therapeutics Inc's market capitalization history from 2015 to 2026. Data shows change from $242.62 Million to $153.81 Million (-4.67% CAGR).

Index Memberships

Karyopharm Therapeutics Inc is a constituent of 2 market indices:

Index Total Market Cap Weight (%) Rank by Market Cap
NASDAQ Health Care
IXHC
$2.20 Trillion 0.01% #462 of 976
NASDAQ Composite
IXIC
$32.97 Trillion 0.00% #1596 of 3165

Weight: Karyopharm Therapeutics Inc's market cap as a percentage of total index value. Rank: Position among all constituents by market cap.

Karyopharm Therapeutics Inc Market Cap to Earnings & Revenue Ratios Timeline

This chart shows how Karyopharm Therapeutics Inc's valuation ratios have evolved. The Price to Sales (P/S) ratio compares market cap to revenue, while the Price to Earnings (P/E) ratio compares market cap to net income. Lower values may indicate a more undervalued company relative to its financial performance.

Latest Price to Sales (P/S) Ratio

0.92x

Karyopharm Therapeutics Inc's market cap is 0.92 times its annual revenue

Industry average:
1740.90x
Lower than industry average

Latest Price to Earnings (P/E) Ratio

N/A

P/E ratio not applicable due to negative or zero earnings

What These Ratios Tell Investors:
  • Price to Sales (P/S) Ratio: Shows how much investors are paying for each dollar of the company's sales. Lower P/S ratios may indicate undervaluation.
  • Price to Earnings (P/E) Ratio: Shows how much investors are paying for each dollar of the company's earnings. This is one of the most common valuation metrics.
  • Trends in these ratios over time can indicate changing investor sentiment about the company's future growth prospects.
  • Industry comparison provides context for whether the company is valued higher or lower than peers.
Year Market Cap (USD) Revenue (USD) Net Income (USD) P/S Ratio P/E Ratio
2016 $172.12 Million $154.00K -$109.58 Million 1117.68x N/A
2017 $175.79 Million $1.60 Million -$128.98 Million 109.52x N/A
2018 $171.57 Million $30.34 Million -$178.41 Million 5.66x N/A
2019 $351.02 Million $40.89 Million -$199.59 Million 8.58x N/A
2020 $283.45 Million $108.08 Million -$196.27 Million 2.62x N/A
2021 $117.74 Million $209.82 Million -$124.09 Million 0.56x N/A
2022 $62.26 Million $157.07 Million -$165.29 Million 0.40x N/A
2023 $15.84 Million $146.03 Million -$143.10 Million 0.11x N/A
2024 $12.38 Million $145.24 Million -$76.42 Million 0.09x N/A
2025 $134.77 Million $146.07 Million -$196.04 Million 0.92x N/A

Competitor Companies of KPTI by Market Capitalization

Companies near Karyopharm Therapeutics Inc in the global market cap rankings as of March 19, 2026.

Key companies related to Karyopharm Therapeutics Inc by market ranking:

  • Vertex Pharmaceuticals Inc (NASDAQ:VRTX): Ranked #165 globally with a market cap of $114.33 Billion USD.
  • Regeneron Pharmaceuticals Inc (NASDAQ:REGN): Ranked #285 globally with a market cap of $73.32 Billion USD.
  • CSL Limited (PINK:CMXHF): Ranked #340 globally with a market cap of $63.46 Billion USD.
  • argenx SE (OTCGREY:ARGNF): Ranked #497 globally with a market cap of $42.99 Billion USD.

Market capitalization comparison (in billions USD)
Rank Company Symbol Market Cap Price
#165 Vertex Pharmaceuticals Inc NASDAQ:VRTX $114.33 Billion $451.59
#285 Regeneron Pharmaceuticals Inc NASDAQ:REGN $73.32 Billion $744.12
#340 CSL Limited PINK:CMXHF $63.46 Billion $149.87
#497 argenx SE OTCGREY:ARGNF $42.99 Billion $697.42

Karyopharm Therapeutics Inc Historical Marketcap From 2015 to 2026

Between 2015 and today, Karyopharm Therapeutics Inc's market cap moved from $242.62 Million to $ 153.81 Million, with a yearly change of -4.67%.

Year Market Cap Change (%)
2026 $153.81 Million +14.13%
2025 $134.77 Million +988.27%
2024 $12.38 Million -21.82%
2023 $15.84 Million -74.56%
2022 $62.26 Million -47.12%
2021 $117.74 Million -58.46%
2020 $283.45 Million -19.25%
2019 $351.02 Million +104.59%
2018 $171.57 Million -2.40%
2017 $175.79 Million +2.13%
2016 $172.12 Million -29.06%
2015 $242.62 Million --

End of Day Market Cap According to Different Sources

On Mar 19th, 2026 the market cap of Karyopharm Therapeutics Inc was reported to be:

Source Market Cap
Yahoo Finance $153.81 Million USD
MoneyControl $153.81 Million USD
MarketWatch $153.81 Million USD
marketcap.company $153.81 Million USD
Reuters $153.81 Million USD

Market cap values may vary slightly between sources due to differences in calculation methods, timing, and data refresh rates.