Vertex Pharmaceuticals Inc (NASDAQ:VRTX) — Market Cap & Net Worth

$107.56 Billion USD  · Rank #223

Market Cap & Net Worth: Vertex Pharmaceuticals Inc (VRTX)

Vertex Pharmaceuticals Inc (NASDAQ:VRTX) has a market capitalization of $107.56 Billion ($107.56 Billion) as of May 3, 2026. Listed on the NASDAQ stock exchange, this USA-based company holds position #223 globally and #118 in its home market, demonstrating a -2.57% decrease in market value over the past year.

Market capitalization, also known as net worth in stock markets, is calculated by multiplying Vertex Pharmaceuticals Inc's stock price $423.92 by its total outstanding shares 253718831 (253.72 Million). Analyse how efficiently does Vertex Pharmaceuticals Inc generate cash to see how efficiently the company converts income to cash.

Vertex Pharmaceuticals Inc Market Cap History: 2015 to 2026

Vertex Pharmaceuticals Inc's market capitalization history from 2015 to 2026. Data shows growth from $31.93 Billion to $107.56 Billion (13.09% CAGR).

Index Memberships

Vertex Pharmaceuticals Inc is a constituent of 7 market indices:

Index Total Market Cap Weight (%) Rank by Market Cap
ARCA Biotechnology
BTK
$910.33 Billion 11.82% #3 of 30
Dow Jones Biotechnology
DJUSBT
$1.09 Trillion 9.88% #4 of 39
S&P 500 Index
GSPC
$59.46 Trillion 0.27% #98 of 503
NASDAQ Health Care
IXHC
$2.41 Trillion 4.46% #5 of 976
NASDAQ Composite
IXIC
$38.77 Trillion 0.28% #41 of 3165
NASDAQ Biotechnology
NBI
$1.67 Trillion 6.45% #4 of 263
Nasdaq 100
NDX
$32.64 Trillion 0.33% #40 of 101

Weight: Vertex Pharmaceuticals Inc's market cap as a percentage of total index value. Rank: Position among all constituents by market cap.

Vertex Pharmaceuticals Inc Market Cap to Earnings & Revenue Ratios Timeline

This chart shows how Vertex Pharmaceuticals Inc's valuation ratios have evolved. The Price to Sales (P/S) ratio compares market cap to revenue, while the Price to Earnings (P/E) ratio compares market cap to net income. Lower values may indicate a more undervalued company relative to its financial performance.

Latest Price to Sales (P/S) Ratio

9.58x

Vertex Pharmaceuticals Inc's market cap is 9.58 times its annual revenue

Industry average: 3784.39x Lower than industry average

Latest Price to Earnings (P/E) Ratio

29.10x

Vertex Pharmaceuticals Inc's market cap is 29.10 times its annual earnings

Industry average: 0.19x Higher than industry average

What These Ratios Tell Investors:

  • Price to Sales (P/S) Ratio: Shows how much investors are paying for each dollar of the company's sales. Lower P/S ratios may indicate undervaluation.
  • Price to Earnings (P/E) Ratio: Shows how much investors are paying for each dollar of the company's earnings. This is one of the most common valuation metrics.
  • Trends in these ratios over time can indicate changing investor sentiment about the company's future growth prospects.
  • Industry comparison provides context for whether the company is valued higher or lower than peers.
Year Market Cap (USD) Revenue (USD) Net Income (USD) P/S Ratio P/E Ratio
2016 $18.69 Billion $1.70 Billion -$112.05 Million 10.98x N/A
2017 $38.02 Billion $2.49 Billion $263.48 Million 15.28x 144.31x
2018 $42.04 Billion $3.05 Billion $2.10 Billion 13.80x 20.05x
2019 $55.55 Billion $4.16 Billion $1.18 Billion 13.34x 47.21x
2020 $59.96 Billion $6.21 Billion $2.71 Billion 9.66x 22.11x
2021 $55.72 Billion $7.57 Billion $2.34 Billion 7.36x 23.79x
2022 $73.27 Billion $8.93 Billion $3.32 Billion 8.20x 22.06x
2023 $103.24 Billion $9.87 Billion $3.62 Billion 10.46x 28.52x
2024 $102.17 Billion $11.02 Billion -$535.60 Million 9.27x N/A
2025 $115.03 Billion $12.00 Billion $3.95 Billion 9.58x 29.10x

Competitor Companies of VRTX by Market Capitalization

Companies near Vertex Pharmaceuticals Inc in the global market cap rankings as of May 3, 2026.

Key companies related to Vertex Pharmaceuticals Inc by market ranking:

  • Regeneron Pharmaceuticals Inc (NASDAQ:REGN): Ranked #367 globally with a market cap of $72.88 Billion USD.
  • UCB SA (BR:UCB): Ranked #517 globally with a market cap of $51.45 Billion USD ( €44.01 Billion EUR).
  • argenx NV ADR (NASDAQ:ARGX): Ranked #568 globally with a market cap of $45.97 Billion USD.
  • UCB S.A. UNSP.ADR 1/2 (F:UNC0): Ranked #585 globally with a market cap of $44.84 Billion USD ( €38.35 Billion EUR).
Market capitalization comparison (in billions USD)
Rank Company Symbol Market Cap Price
#367 Regeneron Pharmaceuticals Inc NASDAQ:REGN $72.88 Billion $701.42
#517 UCB SA BR:UCB $51.45 Billion €231.20
#568 argenx NV ADR NASDAQ:ARGX $45.97 Billion $787.95
#585 UCB S.A. UNSP.ADR 1/2 F:UNC0 $44.84 Billion €120.00

Vertex Pharmaceuticals Inc Historical Marketcap From 2015 to 2026

Between 2015 and today, Vertex Pharmaceuticals Inc's market cap moved from $31.93 Billion to $ 107.56 Billion, with a yearly change of 13.09%.

Year Market Cap Change (%)
2026 $107.56 Billion -6.49%
2025 $115.03 Billion +12.58%
2024 $102.17 Billion -1.03%
2023 $103.24 Billion +40.90%
2022 $73.27 Billion +31.50%
2021 $55.72 Billion -7.08%
2020 $59.96 Billion +7.94%
2019 $55.55 Billion +32.13%
2018 $42.04 Billion +10.58%
2017 $38.02 Billion +103.42%
2016 $18.69 Billion -41.45%
2015 $31.93 Billion --

End of Day Market Cap According to Different Sources

On May 2nd, 2026 the market cap of Vertex Pharmaceuticals Inc was reported to be:

Source Market Cap
Yahoo Finance $107.56 Billion USD
MoneyControl $107.56 Billion USD
MarketWatch $107.56 Billion USD
marketcap.company $107.56 Billion USD
Reuters $107.56 Billion USD

Market cap values may vary slightly between sources due to differences in calculation methods, timing, and data refresh rates.

About Vertex Pharmaceuticals Inc

NASDAQ:VRTX USA Biotechnology
Market Cap
$107.56 Billion
Market Cap Rank
#223 Global
#118 in USA
Share Price
$423.92
Change (1 day)
-0.81%
52-Week Range
$366.54 - $500.19
All Time High
$516.74
About

Vertex Pharmaceuticals Incorporated, a biotechnology company, engages in developing and commercializing therapies for treating cystic fibrosis (CF). It markets TRIKAFTA/KAFTRIO for people with CF with at least one F508del mutation for 2 years of age and older; ALYFTREK for the treatment for people with CF 6 years of age and older; SYMDEKO/SYMKEVI for treatment of patients with CF 6 years of age a… Read more