Vertex Pharmaceuticals Inc (NASDAQ:VRTX) — Market Cap & Net Worth

$130.90 Billion USD  · Rank #186

Market Cap & Net Worth: Vertex Pharmaceuticals Inc (VRTX)

Vertex Pharmaceuticals Inc (NASDAQ:VRTX) has a market capitalization of $130.90 Billion ($130.90 Billion) as of September 15, 2026. Listed on the NASDAQ stock exchange, this USA-based company holds position #186 globally and #101 in its home market, demonstrating a -6.89% decrease in market value over the past year.

Market capitalization, also known as net worth in stock markets, is calculated by multiplying Vertex Pharmaceuticals Inc's stock price $519.51 by its total outstanding shares 253460924 (253.46 Million). Also see Vertex Pharmaceuticals Inc (VRTX) total assets for a full breakdown of the balance sheet.

Vertex Pharmaceuticals Inc Market Cap History: 2015 to 2026

Vertex Pharmaceuticals Inc's market capitalization history from 2015 to 2026. Data shows growth from $31.89 Billion to $131.68 Billion (14.74% CAGR). Also see Vertex Pharmaceuticals Inc operating cash flow efficiency for how efficiently the company converts equity into cash flow.

Index Memberships

Vertex Pharmaceuticals Inc is a constituent of 7 market indices:

Index Total Market Cap Weight (%) Rank by Market Cap
ARCA Biotechnology
BTK
$1.06 Trillion 12.36% #3 of 30
Dow Jones Biotechnology
DJUSBT
$1.16 Trillion 11.24% #4 of 39
S&P 500 Index
GSPC
$63.09 Trillion 0.27% #82 of 503
NASDAQ Health Care
IXHC
$2.68 Trillion 4.89% #5 of 976
NASDAQ Composite
IXIC
$41.94 Trillion 0.31% #37 of 3165
NASDAQ Biotechnology
NBI
$1.89 Trillion 6.93% #4 of 263
Nasdaq 100
NDX
$35.22 Trillion 0.37% #34 of 101

Weight: Vertex Pharmaceuticals Inc's market cap as a percentage of total index value. Rank: Position among all constituents by market cap.

Vertex Pharmaceuticals Inc Market Cap to Earnings & Revenue Ratios Timeline

This chart shows how Vertex Pharmaceuticals Inc's valuation ratios have evolved. The Price to Sales (P/S) ratio compares market cap to revenue, while the Price to Earnings (P/E) ratio compares market cap to net income. Lower values may indicate a more undervalued company relative to its financial performance. Check latest Vertex Pharmaceuticals Inc stock price today for real-time trading data and today's change.

Latest Price to Sales (P/S) Ratio

9.52x

Vertex Pharmaceuticals Inc's market cap is 9.52 times its annual revenue

Industry average: 3828.65x Lower than industry average

Latest Price to Earnings (P/E) Ratio

29.07x

Vertex Pharmaceuticals Inc's market cap is 29.07 times its annual earnings

Industry average: 1.76x Higher than industry average

What These Ratios Tell Investors:

  • Price to Sales (P/S) Ratio: Shows how much investors are paying for each dollar of the company's sales. Lower P/S ratios may indicate undervaluation.
  • Price to Earnings (P/E) Ratio: Shows how much investors are paying for each dollar of the company's earnings. This is one of the most common valuation metrics.
  • Trends in these ratios over time can indicate changing investor sentiment about the company's future growth prospects.
  • Industry comparison provides context for whether the company is valued higher or lower than peers.
Year Market Cap (USD) Revenue (USD) Net Income (USD) P/S Ratio P/E Ratio
2016 $18.67 Billion $1.70 Billion -$112.05 Million 10.97x N/A
2017 $37.98 Billion $2.49 Billion $263.48 Million 15.26x 144.16x
2018 $42.00 Billion $3.05 Billion $2.10 Billion 13.78x 20.03x
2019 $55.50 Billion $4.16 Billion $1.18 Billion 13.33x 47.16x
2020 $59.90 Billion $6.21 Billion $2.71 Billion 9.65x 22.09x
2021 $55.66 Billion $7.57 Billion $2.34 Billion 7.35x 23.77x
2022 $73.19 Billion $8.93 Billion $3.32 Billion 8.20x 22.03x
2023 $103.13 Billion $9.87 Billion $3.62 Billion 10.45x 28.49x
2024 $102.07 Billion $11.02 Billion -$535.60 Million 9.26x N/A
2025 $114.91 Billion $12.07 Billion $3.95 Billion 9.52x 29.07x

Competitor Companies of VRTX by Market Capitalization

Companies near Vertex Pharmaceuticals Inc in the global market cap rankings as of September 15, 2026. Review VRTX intangible-adjusted equity ratio to assess the quality of the company's equity after excluding intangible assets.

Key companies related to Vertex Pharmaceuticals Inc by market ranking:

  • Regeneron Pharmaceuticals Inc (NASDAQ:REGN): Ranked #338 globally with a market cap of $80.28 Billion USD.
  • CSL Ltd (AU:CSL): Ranked #463 globally with a market cap of $58.90 Billion USD ( AU$83.24 Billion AUD).
  • Moderna Inc (NASDAQ:MRNA): Ranked #509 globally with a market cap of $54.14 Billion USD.
  • Argen-X (BR:ARGX): Ranked #573 globally with a market cap of $47.46 Billion USD ( €40.60 Billion EUR).
Market capitalization comparison (in billions USD)
Rank Company Symbol Market Cap Price
#338 Regeneron Pharmaceuticals Inc NASDAQ:REGN $80.28 Billion $793.74
#463 CSL Ltd AU:CSL $58.90 Billion AU$171.57
#509 Moderna Inc NASDAQ:MRNA $54.14 Billion $146.69
#573 Argen-X BR:ARGX $47.46 Billion €867.80

Vertex Pharmaceuticals Inc Historical Marketcap From 2015 to 2026

Between 2015 and today, Vertex Pharmaceuticals Inc's market cap moved from $31.89 Billion to $ 131.68 Billion, with a yearly change of 14.74%.

Year Market Cap Change (%)
2026 $131.68 Billion +14.59%
2025 $114.91 Billion +12.58%
2024 $102.07 Billion -1.03%
2023 $103.13 Billion +40.90%
2022 $73.19 Billion +31.50%
2021 $55.66 Billion -7.08%
2020 $59.90 Billion +7.94%
2019 $55.50 Billion +32.13%
2018 $42.00 Billion +10.58%
2017 $37.98 Billion +103.42%
2016 $18.67 Billion -41.45%
2015 $31.89 Billion --

End of Day Market Cap According to Different Sources

On Sep 15th, 2026 the market cap of Vertex Pharmaceuticals Inc was reported to be:

Source Market Cap
Yahoo Finance $130.90 Billion USD
MoneyControl $130.90 Billion USD
MarketWatch $130.90 Billion USD
marketcap.company $130.90 Billion USD
Reuters $130.90 Billion USD

Market cap values may vary slightly between sources due to differences in calculation methods, timing, and data refresh rates.

About Vertex Pharmaceuticals Inc

NASDAQ:VRTX USA Biotechnology
Market Cap
$131.68 Billion
Market Cap Rank
#186 Global
#101 in USA
Share Price
$519.51
Change (1 day)
+0.79%
52-Week Range
$376.62 - $557.96
All Time High
$557.96
About

Vertex Pharmaceuticals Incorporated operates as a biotechnology company in the United States, Europe, and internationally. The company offers transformative medicines for people with serious diseases with a focus on specialty markets, such as cystic fibrosis (CF), sickle cell disease (SCD), transfusion dependent beta thalassemia (TDT), and acute pain. It markets TRIKAFTA/KAFTRIO for people with C… Read more