Spruce Biosciences, Inc. Common Stock

NASDAQ:SPRB USA Biotechnology
Market Cap
$68.82 Million
Market Cap Rank
#22868 Global
#8040 in USA
Share Price
$64.30
Change (1 day)
+5.50%
52-Week Range
$0.08 - $100.00
All Time High
$100.00
About

Spruce Biosciences, Inc. is a biopharmaceutical company focused on developing and commercializing novel therapies for neurological disorders. The company develops TA-ERT, a fusion protein comprised of recombinant human alpha-N-acetylglucosaminidase, which is an enzyme replacement therapy for patients with Sanfilippo Syndrome Type B. It also develops Tildacerfont for treating a highly debilitating… Read more

Market Cap & Net Worth: Spruce Biosciences, Inc. Common Stock (SPRB)

Spruce Biosciences, Inc. Common Stock (NASDAQ:SPRB) has a market capitalization of $68.82 Million ($68.82 Million) as of March 18, 2026. Listed on the NASDAQ stock exchange, this USA-based company holds position #22868 globally and #8040 in its home market, demonstrating a 3.53% increase in market value over the past year.

Market capitalization, also known as net worth in stock markets, is calculated by multiplying Spruce Biosciences, Inc. Common Stock's stock price $64.30 by its total outstanding shares 1070370 (1.07 Million).

Spruce Biosciences, Inc. Common Stock Market Cap History: 2020 to 2026

Spruce Biosciences, Inc. Common Stock's market capitalization history from 2020 to 2026. Data shows growth from $26.02 Million to $68.82 Million (27.71% CAGR).

Index Memberships

Spruce Biosciences, Inc. Common Stock is a constituent of 2 market indices:

Index Total Market Cap Weight (%) Rank by Market Cap
NASDAQ Health Care
IXHC
$2.24 Trillion 0.00% #611 of 976
NASDAQ Composite
IXIC
$33.39 Trillion 0.00% #2018 of 3165

Weight: Spruce Biosciences, Inc. Common Stock's market cap as a percentage of total index value. Rank: Position among all constituents by market cap.

Spruce Biosciences, Inc. Common Stock Market Cap to Earnings & Revenue Ratios Timeline

This chart shows how Spruce Biosciences, Inc. Common Stock's valuation ratios have evolved. The Price to Sales (P/S) ratio compares market cap to revenue, while the Price to Earnings (P/E) ratio compares market cap to net income. Lower values may indicate a more undervalued company relative to its financial performance.

Latest Price to Sales (P/S) Ratio

0.09x

Spruce Biosciences, Inc. Common Stock's market cap is 0.09 times its annual revenue

Industry average:
1728.56x
Lower than industry average

Latest Price to Earnings (P/E) Ratio

N/A

P/E ratio not applicable due to negative or zero earnings

What These Ratios Tell Investors:
  • Price to Sales (P/S) Ratio: Shows how much investors are paying for each dollar of the company's sales. Lower P/S ratios may indicate undervaluation.
  • Price to Earnings (P/E) Ratio: Shows how much investors are paying for each dollar of the company's earnings. This is one of the most common valuation metrics.
  • Trends in these ratios over time can indicate changing investor sentiment about the company's future growth prospects.
  • Industry comparison provides context for whether the company is valued higher or lower than peers.
Year Market Cap (USD) Revenue (USD) Net Income (USD) P/S Ratio P/E Ratio
2022 $1.17 Million $1.96 Million -$46.18 Million 0.60x N/A
2023 $3.14 Million $10.09 Million -$47.92 Million 0.31x N/A
2024 $449.56K $4.91 Million -$53.04 Million 0.09x N/A

Competitor Companies of SPRB by Market Capitalization

Companies near Spruce Biosciences, Inc. Common Stock in the global market cap rankings as of March 18, 2026.

Key companies related to Spruce Biosciences, Inc. Common Stock by market ranking:

  • Vertex Pharmaceuticals Inc (NASDAQ:VRTX): Ranked #162 globally with a market cap of $117.09 Billion USD.
  • Regeneron Pharmaceuticals Inc (NASDAQ:REGN): Ranked #281 globally with a market cap of $74.80 Billion USD.
  • CSL Limited (PINK:CMXHF): Ranked #344 globally with a market cap of $63.46 Billion USD.
  • argenx SE (OTCGREY:ARGNF): Ranked #500 globally with a market cap of $42.99 Billion USD.

Market capitalization comparison (in billions USD)
Rank Company Symbol Market Cap Price
#162 Vertex Pharmaceuticals Inc NASDAQ:VRTX $117.09 Billion $462.49
#281 Regeneron Pharmaceuticals Inc NASDAQ:REGN $74.80 Billion $759.05
#344 CSL Limited PINK:CMXHF $63.46 Billion $149.87
#500 argenx SE OTCGREY:ARGNF $42.99 Billion $697.42

Spruce Biosciences, Inc. Common Stock Historical Marketcap From 2020 to 2026

Between 2020 and today, Spruce Biosciences, Inc. Common Stock's market cap moved from $26.02 Million to $ 68.82 Million, with a yearly change of 27.71%.

Year Market Cap Change (%)
2026 $68.82 Million -26.19%
2025 $93.24 Million +20640.48%
2024 $449.56K -85.67%
2023 $3.14 Million +167.09%
2022 $1.17 Million -75.40%
2021 $4.77 Million -81.65%
2020 $26.02 Million --

End of Day Market Cap According to Different Sources

On Mar 18th, 2026 the market cap of Spruce Biosciences, Inc. Common Stock was reported to be:

Source Market Cap
Yahoo Finance $68.82 Million USD
MoneyControl $68.82 Million USD
MarketWatch $68.82 Million USD
marketcap.company $68.82 Million USD
Reuters $68.82 Million USD

Market cap values may vary slightly between sources due to differences in calculation methods, timing, and data refresh rates.