Apellis Pharmaceuticals Inc

NASDAQ:APLS USA Biotechnology
Market Cap
$2.41 Billion
Market Cap Rank
#5684 Global
#3319 in USA
Share Price
$18.82
Change (1 day)
-0.26%
52-Week Range
$16.36 - $30.05
All Time High
$93.31
About

Apellis Pharmaceuticals, Inc., a commercial-stage biopharmaceutical company, focuses on the discovery, development, and commercialization of novel therapeutic compounds to treat diseases with high unmet needs. It offers EMPAVELI for the treatment of paroxysmal nocturnal hemoglobinuria; and SYFOVRE for treating geographic atrophy secondary to age-related macular degeneration and geographic atrophy… Read more

Market Cap & Net Worth: Apellis Pharmaceuticals Inc (APLS)

Apellis Pharmaceuticals Inc (NASDAQ:APLS) has a market capitalization of $2.41 Billion ($2.41 Billion) as of March 19, 2026. Listed on the NASDAQ stock exchange, this USA-based company holds position #5684 globally and #3319 in its home market, demonstrating a -5.85% decrease in market value over the past year.

Market capitalization, also known as net worth in stock markets, is calculated by multiplying Apellis Pharmaceuticals Inc's stock price $18.82 by its total outstanding shares 127829909 (127.83 Million).

Apellis Pharmaceuticals Inc Market Cap History: 2017 to 2026

Apellis Pharmaceuticals Inc's market capitalization history from 2017 to 2026. Data shows growth from $2.77 Billion to $2.41 Billion (3.58% CAGR).

Index Memberships

Apellis Pharmaceuticals Inc is a constituent of 3 market indices:

Index Total Market Cap Weight (%) Rank by Market Cap
NASDAQ Health Care
IXHC
$2.24 Trillion 0.07% #155 of 976
NASDAQ Composite
IXIC
$33.39 Trillion 0.00% #673 of 3165
NASDAQ Biotechnology
NBI
$1.54 Trillion 0.10% #101 of 263

Weight: Apellis Pharmaceuticals Inc's market cap as a percentage of total index value. Rank: Position among all constituents by market cap.

Apellis Pharmaceuticals Inc Market Cap to Earnings & Revenue Ratios Timeline

This chart shows how Apellis Pharmaceuticals Inc's valuation ratios have evolved. The Price to Sales (P/S) ratio compares market cap to revenue, while the Price to Earnings (P/E) ratio compares market cap to net income. Lower values may indicate a more undervalued company relative to its financial performance.

Latest Price to Sales (P/S) Ratio

3.20x

Apellis Pharmaceuticals Inc's market cap is 3.20 times its annual revenue

Industry average:
1728.56x
Lower than industry average

Latest Price to Earnings (P/E) Ratio

143.43x

Apellis Pharmaceuticals Inc's market cap is 143.43 times its annual earnings

Industry average:
0.11x
Higher than industry average
What These Ratios Tell Investors:
  • Price to Sales (P/S) Ratio: Shows how much investors are paying for each dollar of the company's sales. Lower P/S ratios may indicate undervaluation.
  • Price to Earnings (P/E) Ratio: Shows how much investors are paying for each dollar of the company's earnings. This is one of the most common valuation metrics.
  • Trends in these ratios over time can indicate changing investor sentiment about the company's future growth prospects.
  • Industry comparison provides context for whether the company is valued higher or lower than peers.
Year Market Cap (USD) Revenue (USD) Net Income (USD) P/S Ratio P/E Ratio
2020 $7.31 Billion $250.65 Million -$344.87 Million 29.17x N/A
2021 $6.04 Billion $66.56 Million -$746.35 Million 90.80x N/A
2022 $6.61 Billion $75.42 Million -$652.17 Million 87.64x N/A
2023 $7.65 Billion $396.59 Million -$528.63 Million 19.29x N/A
2024 $4.08 Billion $781.37 Million -$197.88 Million 5.22x N/A
2025 $3.21 Billion $1.00 Billion $22.39 Million 3.20x 143.43x

Competitor Companies of APLS by Market Capitalization

Companies near Apellis Pharmaceuticals Inc in the global market cap rankings as of March 19, 2026.

Key companies related to Apellis Pharmaceuticals Inc by market ranking:

  • Vertex Pharmaceuticals Inc (NASDAQ:VRTX): Ranked #162 globally with a market cap of $117.09 Billion USD.
  • Regeneron Pharmaceuticals Inc (NASDAQ:REGN): Ranked #281 globally with a market cap of $74.80 Billion USD.
  • CSL Limited (PINK:CMXHF): Ranked #344 globally with a market cap of $63.46 Billion USD.
  • argenx SE (OTCGREY:ARGNF): Ranked #500 globally with a market cap of $42.99 Billion USD.

Market capitalization comparison (in billions USD)
Rank Company Symbol Market Cap Price
#162 Vertex Pharmaceuticals Inc NASDAQ:VRTX $117.09 Billion $462.49
#281 Regeneron Pharmaceuticals Inc NASDAQ:REGN $74.80 Billion $759.05
#344 CSL Limited PINK:CMXHF $63.46 Billion $149.87
#500 argenx SE OTCGREY:ARGNF $42.99 Billion $697.42

Apellis Pharmaceuticals Inc Historical Marketcap From 2017 to 2026

Between 2017 and today, Apellis Pharmaceuticals Inc's market cap moved from $2.77 Billion to $ 2.41 Billion, with a yearly change of 3.58%.

Year Market Cap Change (%)
2026 $2.41 Billion -25.08%
2025 $3.21 Billion -21.28%
2024 $4.08 Billion -46.69%
2023 $7.65 Billion +15.76%
2022 $6.61 Billion +9.37%
2021 $6.04 Billion -17.34%
2020 $7.31 Billion +86.81%
2019 $3.91 Billion +132.15%
2018 $1.69 Billion -39.22%
2017 $2.77 Billion --

End of Day Market Cap According to Different Sources

On Mar 18th, 2026 the market cap of Apellis Pharmaceuticals Inc was reported to be:

Source Market Cap
Yahoo Finance $2.41 Billion USD
MoneyControl $2.41 Billion USD
MarketWatch $2.41 Billion USD
marketcap.company $2.41 Billion USD
Reuters $2.41 Billion USD

Market cap values may vary slightly between sources due to differences in calculation methods, timing, and data refresh rates.