NASDAQ Biotechnology Index (NBI) Companies by Market Cap
The NASDAQ Biotechnology Index (NBI) tracks 263 constituent companies with a combined market cap of $1.85 Trillion, covering the largest publicly traded companies in USA. This ranking lists all NBI index holdings ordered by market capitalization — from the largest index heavyweights to smaller constituents. Updated daily with live market data.
Total Market Cap (USD)
$1.85 Trillion
Constituent Companies
263
Index Country
USA
| Rank | Company | Weight (%) | Market Cap (USD) | Sector | Industry | Price | 24h Change |
|---|---|---|---|---|---|---|---|
| 1 |
AstraZeneca PLC
NASDAQ:AZN |
% | $282.04 Billion | Healthcare | Drug Manufacturers - General | $187.03 | -1.43% |
| 2 |
Amgen Inc
NASDAQ:AMGN |
% | $198.99 Billion | Healthcare | Drug Manufacturers - General | $442.24 | -0.36% |
| 3 |
Gilead Sciences Inc
NASDAQ:GILD |
% | $182.68 Billion | Healthcare | Drug Manufacturers - General | $148.77 | +1.38% |
| 4 |
Vertex Pharmaceuticals Inc
NASDAQ:VRTX |
% | $130.90 Billion | Healthcare | Biotechnology | $552.85 | +0.96% |
| 5 |
Regeneron Pharmaceuticals Inc
NASDAQ:REGN |
% | $83.19 Billion | Healthcare | Biotechnology | $833.56 | +0.61% |
| 6 |
argenx NV ADR
NASDAQ:ARGX |
% | $45.97 Billion | Healthcare | Biotechnology | $787.95 | -0.66% |
| 7 |
Revolution Medicines Inc
NASDAQ:RVMD |
% | $43.97 Billion | Healthcare | Biotechnology | $211.38 | -0.09% |
| 8 |
Alnylam Pharmaceuticals Inc
NASDAQ:ALNY |
% | $31.84 Billion | Healthcare | Biotechnology | $240.08 | +1.72% |
| 9 |
Biogen Inc
NASDAQ:BIIB |
% | $27.74 Billion | Healthcare | Drug Manufacturers - General | $220.77 | +1.21% |
| 10 |
Royalty Pharma Plc
NASDAQ:RPRX |
% | $27.51 Billion | Healthcare | Biotechnology | $62.07 | +1.21% |
| 11 |
Insmed Inc
NASDAQ:INSM |
% | $26.42 Billion | Healthcare | Biotechnology | $123.89 | -0.07% |
| 12 |
Incyte Corporation
NASDAQ:INCY |
% | $24.43 Billion | Healthcare | Biotechnology | $129.72 | +1.36% |
| 13 |
Moderna Inc
NASDAQ:MRNA |
% | $23.88 Billion | Healthcare | Biotechnology | $158.83 | +14.36% |
| 14 |
United Therapeutics Corporation
NASDAQ:UTHR |
% | $21.42 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $518.53 | +1.10% |
| 15 |
Roivant Sciences Ltd
NASDAQ:ROIV |
% | $20.44 Billion | Healthcare | Biotechnology | $36.47 | +0.30% |
| 16 |
Viatris Inc
NASDAQ:VTRS |
% | $18.70 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $16.72 | +1.09% |
| 17 |
Illumina Inc
NASDAQ:ILMN |
% | $18.34 Billion | Healthcare | Diagnostics & Research | $224.99 | +0.79% |
| 18 |
Medpace Holdings Inc
NASDAQ:MEDP |
% | $16.49 Billion | Healthcare | Diagnostics & Research | $614.06 | -0.96% |
| 19 |
Genmab AS
NASDAQ:GMAB |
% | $16.23 Billion | Healthcare | Biotechnology | $34.36 | +4.06% |
| 20 |
Ascendis Pharma AS
NASDAQ:ASND |
% | $14.74 Billion | Healthcare | Biotechnology | $252.99 | +0.41% |
| 21 |
BridgeBio Pharma Inc
NASDAQ:BBIO |
% | $14.42 Billion | Healthcare | Biotechnology | $80.40 | -0.83% |
| 22 |
Jazz Pharmaceuticals PLC
NASDAQ:JAZZ |
% | $14.17 Billion | Healthcare | Biotechnology | $260.23 | +2.26% |
| 23 |
Neurocrine Biosciences Inc
NASDAQ:NBIX |
% | $13.03 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $153.37 | +0.22% |
| 24 |
Guardant Health Inc
NASDAQ:GH |
% | $12.69 Billion | Healthcare | Diagnostics & Research | $164.92 | +1.07% |
| 25 |
Exelixis Inc
NASDAQ:EXEL |
% | $12.17 Billion | Healthcare | Biotechnology | $56.72 | +3.98% |
| 26 |
Madrigal Pharmaceuticals Inc
NASDAQ:MDGL |
% | $11.90 Billion | Healthcare | Biotechnology | $518.74 | -1.97% |
| 27 |
Biomarin Pharmaceutical Inc
NASDAQ:BMRN |
% | $10.93 Billion | Healthcare | Biotechnology | $66.12 | +1.61% |
| 28 |
Axsome Therapeutics Inc
NASDAQ:AXSM |
% | $10.76 Billion | Healthcare | Biotechnology | $205.48 | +0.04% |
| 29 |
Summit Therapeutics PLC
NASDAQ:SMMT |
% | $10.37 Billion | Healthcare | Biotechnology | $13.36 | +4.95% |
| 30 |
Cytokinetics Inc
NASDAQ:CYTK |
% | $10.33 Billion | Healthcare | Biotechnology | $77.46 | +0.48% |
| 31 |
Praxis Precision Medicines Inc
NASDAQ:PRAX |
% | $10.26 Billion | Healthcare | Biotechnology | $368.02 | 0.00% |
| 32 |
Krystal Biotech Inc
NASDAQ:KRYS |
% | $9.72 Billion | Healthcare | Biotechnology | $356.19 | +4.23% |
| 33 |
Ionis Pharmaceuticals Inc
NASDAQ:IONS |
% | $9.39 Billion | Healthcare | Biotechnology | $63.57 | +2.47% |
| 34 |
Tempus AI, Inc. Class A Common Stock
NASDAQ:TEM |
% | $9.34 Billion | Healthcare | Health Information Services | $68.73 | +3.87% |
| 35 |
Arrowhead Pharmaceuticals Inc
NASDAQ:ARWR |
% | $9.19 Billion | Healthcare | Biotechnology | $88.88 | +2.48% |
| 36 |
Spyre Therapeutics Inc.
NASDAQ:SYRE |
% | $9.18 Billion | Healthcare | Biotechnology | $107.36 | +0.67% |
| 37 |
Nuvalent Inc
NASDAQ:NUVL |
% | $9.12 Billion | Healthcare | Biotechnology | $123.96 | +0.00% |
| 38 |
Kymera Therapeutics Inc
NASDAQ:KYMR |
% | $8.84 Billion | Healthcare | Biotechnology | $126.64 | +4.62% |
| 39 |
Halozyme Therapeutics Inc
NASDAQ:HALO |
% | $8.70 Billion | Healthcare | Biotechnology | $109.32 | +0.63% |
| 40 |
Immunovant Inc
NASDAQ:IMVT |
% | $8.64 Billion | Healthcare | Biotechnology | $43.50 | +0.42% |
| 41 |
Blueprint Medicines Corp
NASDAQ:BPMC |
% | $8.36 Billion | Healthcare | Biotechnology | $129.46 | +0.00% |
| 42 |
Apogee Therapeutics, Inc. Common Stock
NASDAQ:APGE |
% | $8.32 Billion | Healthcare | Biotechnology | $134.85 | +0.04% |
| 43 |
Alkermes Plc
NASDAQ:ALKS |
% | $8.26 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $49.21 | +0.70% |
| 44 |
Vaxcyte Inc
NASDAQ:PCVX |
% | $7.65 Billion | Healthcare | Biotechnology | $61.09 | -1.26% |
| 45 |
Verona Pharma PLC ADR
NASDAQ:VRNA |
% | $7.31 Billion | Healthcare | Biotechnology | $86.00 | +0.00% |
| 46 |
Twist Bioscience Corp
NASDAQ:TWST |
% | $7.25 Billion | Healthcare | Diagnostics & Research | $151.42 | +7.54% |
| 47 |
Merus BV
NASDAQ:MRUS |
% | $6.83 Billion | Healthcare | Biotechnology | $90.00 | -7.14% |
| 48 |
Arcellx Inc
NASDAQ:ACLX |
% | $6.73 Billion | Healthcare | Biotechnology | $115.07 | +0.00% |
| 49 |
Erasca Inc
NASDAQ:ERAS |
% | $6.16 Billion | Healthcare | Biotechnology | $17.76 | +0.91% |
| 50 |
Ligand Pharmaceuticals Incorporated
NASDAQ:LGND |
% | $6.11 Billion | Healthcare | Biotechnology | $281.72 | +0.55% |
Complete list of all companies in the NBI index ranked by market capitalization. Track index constituent performance and market values. View all indices