NASDAQ Biotechnology Index (NBI) Companies by Market Cap
The NASDAQ Biotechnology Index (NBI) tracks 263 constituent companies with a combined market cap of $1.84 Trillion, covering the largest publicly traded companies in USA. This ranking lists all NBI index holdings ordered by market capitalization — from the largest index heavyweights to smaller constituents. Updated daily with live market data.
Total Market Cap (USD)
$1.84 Trillion
Constituent Companies
263
Index Country
USA
| Rank | Company | Weight (%) | Market Cap (USD) | Sector | Industry | Price | 24h Change |
|---|---|---|---|---|---|---|---|
| 1 |
AstraZeneca PLC
NASDAQ:AZN |
% | $282.04 Billion | Healthcare | Drug Manufacturers - General | $187.03 | -1.43% |
| 2 |
Amgen Inc
NASDAQ:AMGN |
% | $198.99 Billion | Healthcare | Drug Manufacturers - General | $414.87 | +1.82% |
| 3 |
Gilead Sciences Inc
NASDAQ:GILD |
% | $182.40 Billion | Healthcare | Drug Manufacturers - General | $151.17 | +2.77% |
| 4 |
Vertex Pharmaceuticals Inc
NASDAQ:VRTX |
% | $129.29 Billion | Healthcare | Biotechnology | $510.08 | +1.36% |
| 5 |
Regeneron Pharmaceuticals Inc
NASDAQ:REGN |
% | $75.50 Billion | Healthcare | Biotechnology | $746.54 | +0.94% |
| 6 |
Moderna Inc
NASDAQ:MRNA |
% | $54.14 Billion | Healthcare | Biotechnology | $225.00 | +14.21% |
| 7 |
argenx NV ADR
NASDAQ:ARGX |
% | $45.97 Billion | Healthcare | Biotechnology | $787.95 | -0.66% |
| 8 |
Revolution Medicines Inc
NASDAQ:RVMD |
% | $40.32 Billion | Healthcare | Biotechnology | $189.76 | +0.87% |
| 9 |
Biogen Inc
NASDAQ:BIIB |
% | $32.27 Billion | Healthcare | Drug Manufacturers - General | $225.71 | +3.33% |
| 10 |
Alnylam Pharmaceuticals Inc
NASDAQ:ALNY |
% | $30.86 Billion | Healthcare | Biotechnology | $232.68 | +3.63% |
| 11 |
Royalty Pharma Plc
NASDAQ:RPRX |
% | $25.24 Billion | Healthcare | Biotechnology | $56.93 | +1.28% |
| 12 |
Incyte Corporation
NASDAQ:INCY |
% | $22.86 Billion | Healthcare | Biotechnology | $112.79 | +0.04% |
| 13 |
Insmed Inc
NASDAQ:INSM |
% | $21.46 Billion | Healthcare | Biotechnology | $100.60 | +0.12% |
| 14 |
United Therapeutics Corporation
NASDAQ:UTHR |
% | $21.32 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $549.16 | +3.07% |
| 15 |
Roivant Sciences Ltd
NASDAQ:ROIV |
% | $20.44 Billion | Healthcare | Biotechnology | $35.44 | +3.60% |
| 16 |
Viatris Inc
NASDAQ:VTRS |
% | $18.70 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $17.64 | +1.15% |
| 17 |
Illumina Inc
NASDAQ:ILMN |
% | $18.34 Billion | Healthcare | Diagnostics & Research | $278.17 | +5.14% |
| 18 |
Medpace Holdings Inc
NASDAQ:MEDP |
% | $16.36 Billion | Healthcare | Diagnostics & Research | $612.05 | +1.55% |
| 19 |
Genmab AS
NASDAQ:GMAB |
% | $16.23 Billion | Healthcare | Biotechnology | $37.07 | +2.83% |
| 20 |
Ascendis Pharma AS
NASDAQ:ASND |
% | $14.16 Billion | Healthcare | Biotechnology | $229.23 | +2.94% |
| 21 |
Summit Therapeutics PLC
NASDAQ:SMMT |
% | $13.99 Billion | Healthcare | Biotechnology | $17.59 | +2.45% |
| 22 |
Jazz Pharmaceuticals PLC
NASDAQ:JAZZ |
% | $13.70 Billion | Healthcare | Biotechnology | $218.42 | -1.81% |
| 23 |
Neurocrine Biosciences Inc
NASDAQ:NBIX |
% | $13.03 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $142.44 | +0.84% |
| 24 |
BridgeBio Pharma Inc
NASDAQ:BBIO |
% | $12.71 Billion | Healthcare | Biotechnology | $65.35 | +0.48% |
| 25 |
Guardant Health Inc
NASDAQ:GH |
% | $12.69 Billion | Healthcare | Diagnostics & Research | $167.47 | +1.15% |
| 26 |
Exelixis Inc
NASDAQ:EXEL |
% | $12.17 Billion | Healthcare | Biotechnology | $59.86 | +1.42% |
| 27 |
Madrigal Pharmaceuticals Inc
NASDAQ:MDGL |
% | $11.90 Billion | Healthcare | Biotechnology | $518.74 | -1.97% |
| 28 |
Tempus AI, Inc. Class A Common Stock
NASDAQ:TEM |
% | $11.06 Billion | Healthcare | Health Information Services | $70.93 | +2.38% |
| 29 |
Biomarin Pharmaceutical Inc
NASDAQ:BMRN |
% | $10.61 Billion | Healthcare | Biotechnology | $54.80 | -0.16% |
| 30 |
Krystal Biotech Inc
NASDAQ:KRYS |
% | $9.72 Billion | Healthcare | Biotechnology | $331.61 | +1.32% |
| 31 |
Vaxcyte Inc
NASDAQ:PCVX |
% | $9.67 Billion | Healthcare | Biotechnology | $71.38 | +9.79% |
| 32 |
Nuvalent Inc
NASDAQ:NUVL |
% | $9.12 Billion | Healthcare | Biotechnology | $123.96 | +0.00% |
| 33 |
Crinetics Pharmaceuticals Inc
NASDAQ:CRNX |
% | $9.01 Billion | Healthcare | Biotechnology | $84.95 | +0.00% |
| 34 |
Kymera Therapeutics Inc
NASDAQ:KYMR |
% | $8.99 Billion | Healthcare | Biotechnology | $112.40 | +2.84% |
| 35 |
Axsome Therapeutics Inc
NASDAQ:AXSM |
% | $8.82 Billion | Healthcare | Biotechnology | $168.35 | -1.02% |
| 36 |
10X Genomics Inc
NASDAQ:TXG |
% | $8.77 Billion | Healthcare | Health Information Services | $80.65 | +4.36% |
| 37 |
Arrowhead Pharmaceuticals Inc
NASDAQ:ARWR |
% | $8.75 Billion | Healthcare | Biotechnology | $62.75 | +3.31% |
| 38 |
Halozyme Therapeutics Inc
NASDAQ:HALO |
% | $8.70 Billion | Healthcare | Biotechnology | $110.42 | +0.53% |
| 39 |
Cytokinetics Inc
NASDAQ:CYTK |
% | $8.62 Billion | Healthcare | Biotechnology | $62.91 | +1.45% |
| 40 |
Apogee Therapeutics, Inc. Common Stock
NASDAQ:APGE |
% | $8.40 Billion | Healthcare | Biotechnology | $135.07 | -0.01% |
| 41 |
Blueprint Medicines Corp
NASDAQ:BPMC |
% | $8.36 Billion | Healthcare | Biotechnology | $129.46 | +0.00% |
| 42 |
Twist Bioscience Corp
NASDAQ:TWST |
% | $8.26 Billion | Healthcare | Diagnostics & Research | $159.78 | +5.08% |
| 43 |
Ionis Pharmaceuticals Inc
NASDAQ:IONS |
% | $7.52 Billion | Healthcare | Biotechnology | $45.28 | +4.57% |
| 44 |
Spyre Therapeutics Inc.
NASDAQ:SYRE |
% | $7.44 Billion | Healthcare | Biotechnology | $85.69 | +7.25% |
| 45 |
Verona Pharma PLC ADR
NASDAQ:VRNA |
% | $7.31 Billion | Healthcare | Biotechnology | $86.00 | +0.00% |
| 46 |
Praxis Precision Medicines Inc
NASDAQ:PRAX |
% | $7.24 Billion | Healthcare | Biotechnology | $259.86 | -1.40% |
| 47 |
Merus BV
NASDAQ:MRUS |
% | $6.83 Billion | Healthcare | Biotechnology | $90.00 | -7.14% |
| 48 |
Alkermes Plc
NASDAQ:ALKS |
% | $6.81 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $40.61 | +1.25% |
| 49 |
Arcellx Inc
NASDAQ:ACLX |
% | $6.73 Billion | Healthcare | Biotechnology | $115.07 | +0.00% |
| 50 |
Ligand Pharmaceuticals Incorporated
NASDAQ:LGND |
% | $6.36 Billion | Healthcare | Biotechnology | $301.81 | +2.31% |
Complete list of all companies in the NBI index ranked by market capitalization. Track index constituent performance and market values. View all indices