NASDAQ Biotechnology Index (NBI) Companies by Market Cap

The NASDAQ Biotechnology Index (NBI) tracks 263 constituent companies with a combined market cap of $1.75 Trillion, covering the largest publicly traded companies in USA. This ranking lists all NBI index holdings ordered by market capitalization — from the largest index heavyweights to smaller constituents. Updated daily with live market data.

Total Market Cap (USD)

$1.75 Trillion

Constituent Companies

263

Index Country

USA
Rank Company Weight (%) Market Cap (USD) Sector Industry Price 24h Change
1 AstraZeneca PLC
NASDAQ:AZN
% $282.04 Billion Healthcare Drug Manufacturers - General $187.03 -1.43%
2 Amgen Inc
NASDAQ:AMGN
% $195.87 Billion Healthcare Drug Manufacturers - General $363.39 -0.06%
3 Gilead Sciences Inc
NASDAQ:GILD
% $161.08 Billion Healthcare Drug Manufacturers - General $129.83 -3.72%
4 Vertex Pharmaceuticals Inc
NASDAQ:VRTX
% $110.45 Billion Healthcare Biotechnology $485.39 -2.24%
5 Regeneron Pharmaceuticals Inc
NASDAQ:REGN
% $64.60 Billion Healthcare Biotechnology $664.52 -0.51%
6 argenx NV ADR
NASDAQ:ARGX
% $45.97 Billion Healthcare Biotechnology $787.95 -0.66%
7 Revolution Medicines Inc
NASDAQ:RVMD
% $39.73 Billion Healthcare Biotechnology $186.88 -2.22%
8 Alnylam Pharmaceuticals Inc
NASDAQ:ALNY
% $39.62 Billion Healthcare Biotechnology $298.76 -4.49%
9 Biogen Inc
NASDAQ:BIIB
% $27.74 Billion Healthcare Drug Manufacturers - General $199.15 +0.12%
10 Royalty Pharma Plc
NASDAQ:RPRX
% $25.01 Billion Healthcare Biotechnology $56.43 -2.64%
11 Insmed Inc
NASDAQ:INSM
% $24.66 Billion Healthcare Biotechnology $115.61 -2.24%
12 United Therapeutics Corporation
NASDAQ:UTHR
% $21.42 Billion Healthcare Drug Manufacturers - Specialty & Generic $547.06 -0.98%
13 Roivant Sciences Ltd
NASDAQ:ROIV
% $20.44 Billion Healthcare Biotechnology $35.97 -2.28%
14 Incyte Corporation
NASDAQ:INCY
% $20.04 Billion Healthcare Biotechnology $116.71 -1.53%
15 Moderna Inc
NASDAQ:MRNA
% $19.49 Billion Healthcare Biotechnology $68.27 -10.83%
16 Viatris Inc
NASDAQ:VTRS
% $18.95 Billion Healthcare Drug Manufacturers - Specialty & Generic $16.27 -0.43%
17 Illumina Inc
NASDAQ:ILMN
% $18.34 Billion Healthcare Diagnostics & Research $190.20 -1.84%
18 Genmab AS
NASDAQ:GMAB
% $16.23 Billion Healthcare Biotechnology $29.00 -2.62%
19 Medpace Holdings Inc
NASDAQ:MEDP
% $15.19 Billion Healthcare Diagnostics & Research $538.23 +0.51%
20 Ascendis Pharma AS
NASDAQ:ASND
% $14.74 Billion Healthcare Biotechnology $270.45 -1.81%
21 BridgeBio Pharma Inc
NASDAQ:BBIO
% $14.42 Billion Healthcare Biotechnology $85.89 -4.75%
22 Jazz Pharmaceuticals PLC
NASDAQ:JAZZ
% $14.17 Billion Healthcare Biotechnology $243.82 -1.25%
23 Neurocrine Biosciences Inc
NASDAQ:NBIX
% $13.03 Billion Healthcare Drug Manufacturers - Specialty & Generic $177.11 -1.91%
24 Guardant Health Inc
NASDAQ:GH
% $12.69 Billion Healthcare Diagnostics & Research $160.05 -2.46%
25 Exelixis Inc
NASDAQ:EXEL
% $12.17 Billion Healthcare Biotechnology $56.50 -1.05%
26 Axsome Therapeutics Inc
NASDAQ:AXSM
% $12.03 Billion Healthcare Biotechnology $233.80 -6.09%
27 Madrigal Pharmaceuticals Inc
NASDAQ:MDGL
% $11.90 Billion Healthcare Biotechnology $518.74 -1.97%
28 Summit Therapeutics PLC
NASDAQ:SMMT
% $10.95 Billion Healthcare Biotechnology $15.25 -1.49%
29 Biomarin Pharmaceutical Inc
NASDAQ:BMRN
% $10.93 Billion Healthcare Biotechnology $59.12 -1.42%
30 Cytokinetics Inc
NASDAQ:CYTK
% $10.33 Billion Healthcare Biotechnology $84.87 -1.39%
31 Kymera Therapeutics Inc
NASDAQ:KYMR
% $9.81 Billion Healthcare Biotechnology $119.35 +0.29%
32 Ionis Pharmaceuticals Inc
NASDAQ:IONS
% $9.44 Billion Healthcare Biotechnology $58.25 -9.38%
33 Tempus AI, Inc. Class A Common Stock
NASDAQ:TEM
% $9.34 Billion Healthcare Health Information Services $58.23 -5.32%
34 Krystal Biotech Inc
NASDAQ:KRYS
% $9.22 Billion Healthcare Biotechnology $365.81 -1.46%
35 Arrowhead Pharmaceuticals Inc
NASDAQ:ARWR
% $9.19 Billion Healthcare Biotechnology $76.40 -9.05%
36 Nuvalent Inc
NASDAQ:NUVL
% $9.11 Billion Healthcare Biotechnology $123.90 +0.06%
37 Halozyme Therapeutics Inc
NASDAQ:HALO
% $8.70 Billion Healthcare Biotechnology $76.20 -3.08%
38 Blueprint Medicines Corp
NASDAQ:BPMC
% $8.36 Billion Healthcare Biotechnology $129.46 +0.14%
39 Vaxcyte Inc
NASDAQ:PCVX
% $7.65 Billion Healthcare Biotechnology $58.21 -2.71%
40 Alkermes Plc
NASDAQ:ALKS
% $7.49 Billion Healthcare Drug Manufacturers - Specialty & Generic $51.94 -3.42%
41 Verona Pharma PLC ADR
NASDAQ:VRNA
% $7.31 Billion Healthcare Biotechnology $86.00 +0.00%
42 Praxis Precision Medicines Inc
NASDAQ:PRAX
% $7.08 Billion Healthcare Biotechnology $324.99 -2.44%
43 Merus BV
NASDAQ:MRUS
% $6.83 Billion Healthcare Biotechnology $90.00 -7.14%
44 Arcellx Inc
NASDAQ:ACLX
% $6.73 Billion Healthcare Biotechnology $115.07 +0.00%
45 Spyre Therapeutics Inc.
NASDAQ:SYRE
% $6.64 Billion Healthcare Biotechnology $97.74 -1.02%
46 Mirum Pharmaceuticals Inc
NASDAQ:MIRM
% $6.53 Billion Healthcare Biotechnology $122.13 -4.36%
47 Apogee Therapeutics, Inc. Common Stock
NASDAQ:APGE
% $6.24 Billion Healthcare Biotechnology $133.65 +0.06%
48 PTC Therapeutics Inc
NASDAQ:PTCT
% $6.11 Billion Healthcare Biotechnology $84.85 -5.25%
49 Centessa Pharmaceuticals PLC ADR
NASDAQ:CNTA
% $6.10 Billion Healthcare Biotechnology $39.43 -0.10%
50 Immunitybio Inc
NASDAQ:IBRX
% $5.96 Billion Healthcare Biotechnology $8.22 -7.33%

Complete list of all companies in the NBI index ranked by market capitalization. Track index constituent performance and market values. View all indices