NASDAQ Biotechnology Index (NBI) Companies by Market Cap

The NASDAQ Biotechnology Index (NBI) tracks 263 constituent companies with a combined market cap of $1.67 Trillion, covering the largest publicly traded companies in USA. This ranking lists all NBI index holdings ordered by market capitalization — from the largest index heavyweights to smaller constituents. Updated daily with live market data.

Total Market Cap (USD)

$1.67 Trillion

Constituent Companies

263

Index Country

USA
Rank Company Weight (%) Market Cap (USD) Sector Industry Price 24h Change
1 AstraZeneca PLC
NASDAQ:AZN
% $286.40 Billion Healthcare Drug Manufacturers - General $184.74 -1.40%
2 Amgen Inc
NASDAQ:AMGN
% $177.77 Billion Healthcare Drug Manufacturers - General $329.82 -4.75%
3 Gilead Sciences Inc
NASDAQ:GILD
% $163.34 Billion Healthcare Drug Manufacturers - General $131.65 +0.62%
4 Vertex Pharmaceuticals Inc
NASDAQ:VRTX
% $107.56 Billion Healthcare Biotechnology $423.92 -0.81%
5 Regeneron Pharmaceuticals Inc
NASDAQ:REGN
% $72.88 Billion Healthcare Biotechnology $701.42 -0.80%
6 argenx NV ADR
NASDAQ:ARGX
% $45.97 Billion Healthcare Biotechnology $787.95 -0.66%
7 Alnylam Pharmaceuticals Inc
NASDAQ:ALNY
% $39.27 Billion Healthcare Biotechnology $296.11 -4.32%
8 Insmed Inc
NASDAQ:INSM
% $28.42 Billion Healthcare Biotechnology $133.26 -2.25%
9 Biogen Inc
NASDAQ:BIIB
% $27.45 Billion Healthcare Drug Manufacturers - General $187.06 -1.17%
10 United Therapeutics Corporation
NASDAQ:UTHR
% $21.42 Billion Healthcare Drug Manufacturers - Specialty & Generic $570.40 -0.17%
11 Royalty Pharma Plc
NASDAQ:RPRX
% $21.19 Billion Healthcare Biotechnology $49.47 -1.24%
12 Roivant Sciences Ltd
NASDAQ:ROIV
% $19.92 Billion Healthcare Biotechnology $27.83 -2.45%
13 Incyte Corporation
NASDAQ:INCY
% $19.29 Billion Healthcare Biotechnology $96.91 +1.72%
14 Revolution Medicines Inc
NASDAQ:RVMD
% $18.62 Billion Healthcare Biotechnology $139.48 -3.22%
15 Illumina Inc
NASDAQ:ILMN
% $18.34 Billion Healthcare Diagnostics & Research $135.78 +7.13%
16 Moderna Inc
NASDAQ:MRNA
% $17.99 Billion Healthcare Biotechnology $45.37 -1.24%
17 Viatris Inc
NASDAQ:VTRS
% $17.32 Billion Healthcare Drug Manufacturers - Specialty & Generic $15.04 +0.67%
18 Genmab AS
NASDAQ:GMAB
% $16.24 Billion Healthcare Biotechnology $26.45 -0.26%
19 Ascendis Pharma AS
NASDAQ:ASND
% $13.56 Billion Healthcare Biotechnology $220.93 -3.68%
20 BridgeBio Pharma Inc
NASDAQ:BBIO
% $13.14 Billion Healthcare Biotechnology $68.56 -3.59%
21 Neurocrine Biosciences Inc
NASDAQ:NBIX
% $13.03 Billion Healthcare Drug Manufacturers - Specialty & Generic $131.78 +0.08%
22 Jazz Pharmaceuticals PLC
NASDAQ:JAZZ
% $12.20 Billion Healthcare Biotechnology $202.72 -0.15%
23 Ionis Pharmaceuticals Inc
NASDAQ:IONS
% $12.19 Billion Healthcare Biotechnology $75.28 +0.70%
24 Medpace Holdings Inc
NASDAQ:MEDP
% $11.92 Billion Healthcare Diagnostics & Research $417.54 -0.27%
25 Madrigal Pharmaceuticals Inc
NASDAQ:MDGL
% $11.90 Billion Healthcare Biotechnology $518.74 -1.97%
26 Exelixis Inc
NASDAQ:EXEL
% $11.34 Billion Healthcare Biotechnology $43.68 -1.75%
27 Summit Therapeutics PLC
NASDAQ:SMMT
% $11.14 Billion Healthcare Biotechnology $16.12 -24.91%
28 Guardant Health Inc
NASDAQ:GH
% $11.02 Billion Healthcare Diagnostics & Research $87.60 +0.60%
29 Biomarin Pharmaceutical Inc
NASDAQ:BMRN
% $10.40 Billion Healthcare Biotechnology $54.06 +0.28%
30 Tempus AI, Inc. Class A Common Stock
NASDAQ:TEM
% $9.34 Billion Healthcare Health Information Services $55.00 -0.87%
31 Arrowhead Pharmaceuticals Inc
NASDAQ:ARWR
% $9.19 Billion Healthcare Biotechnology $74.81 +1.81%
32 Praxis Precision Medicines Inc
NASDAQ:PRAX
% $8.92 Billion Healthcare Biotechnology $324.20 +1.68%
33 Blueprint Medicines Corp
NASDAQ:BPMC
% $8.36 Billion Healthcare Biotechnology $129.46 +0.14%
34 Vaxcyte Inc
NASDAQ:PCVX
% $8.19 Billion Healthcare Biotechnology $56.93 -0.54%
35 Axsome Therapeutics Inc
NASDAQ:AXSM
% $7.88 Billion Healthcare Biotechnology $206.53 -0.59%
36 Krystal Biotech Inc
NASDAQ:KRYS
% $7.71 Billion Healthcare Biotechnology $266.04 +1.44%
37 Halozyme Therapeutics Inc
NASDAQ:HALO
% $7.52 Billion Healthcare Biotechnology $63.96 +0.47%
38 Cytokinetics Inc
NASDAQ:CYTK
% $7.39 Billion Healthcare Biotechnology $63.35 -0.97%
39 Verona Pharma PLC ADR
NASDAQ:VRNA
% $7.31 Billion Healthcare Biotechnology $86.00 +0.00%
40 Merus BV
NASDAQ:MRUS
% $6.83 Billion Healthcare Biotechnology $90.00 -7.14%
41 Nuvalent Inc
NASDAQ:NUVL
% $6.66 Billion Healthcare Biotechnology $99.04 -1.24%
42 Kymera Therapeutics Inc
NASDAQ:KYMR
% $6.32 Billion Healthcare Biotechnology $80.71 -0.44%
43 Centessa Pharmaceuticals PLC ADR
NASDAQ:CNTA
% $6.10 Billion Healthcare Biotechnology $39.43 -0.10%
44 Immunitybio Inc
NASDAQ:IBRX
% $5.96 Billion Healthcare Biotechnology $7.11 +0.14%
45 Cogent Biosciences Inc
NASDAQ:COGT
% $5.86 Billion Healthcare Biotechnology $36.63 +2.35%
46 Mirum Pharmaceuticals Inc
NASDAQ:MIRM
% $5.82 Billion Healthcare Biotechnology $96.53 -0.80%
47 CG Oncology, Inc. Common stock
NASDAQ:CGON
% $5.60 Billion Healthcare Biotechnology $66.27 -0.70%
48 Rhythm Pharmaceuticals Inc
NASDAQ:RYTM
% $5.59 Billion Healthcare Biotechnology $81.81 +0.55%
49 PTC Therapeutics Inc
NASDAQ:PTCT
% $5.39 Billion Healthcare Biotechnology $65.15 +0.14%
50 Immunovant Inc
NASDAQ:IMVT
% $5.24 Billion Healthcare Biotechnology $27.12 -0.09%

Complete list of all companies in the NBI index ranked by market capitalization. Track index constituent performance and market values. View all indices