Protagonist Therapeutics Inc

NASDAQ:PTGX USA Biotechnology
Market Cap
$6.08 Billion
Market Cap Rank
#2844 Global
#1946 in USA
Share Price
$97.23
Change (1 day)
+0.50%
52-Week Range
$40.89 - $97.23
All Time High
$97.23
About

Protagonist Therapeutics, Inc., a biopharmaceutical company, develops peptide therapeutics for hematology and blood disorders, and inflammatory and immunomodulatory diseases. It is developing Rusfertide, an injectable mimetic of hepcidin that is in phase 3 clinical trials for the treatment of polycythemia vera; Icotrokinra, an orally delivered investigational drug which is in phase 3 clinical tri… Read more

Market Cap & Net Worth: Protagonist Therapeutics Inc (PTGX)

Protagonist Therapeutics Inc (NASDAQ:PTGX) has a market capitalization of $6.08 Billion ($6.08 Billion) as of March 19, 2026. Listed on the NASDAQ stock exchange, this USA-based company holds position #2844 globally and #1946 in its home market, demonstrating a 0.59% increase in market value over the past year.

Market capitalization, also known as net worth in stock markets, is calculated by multiplying Protagonist Therapeutics Inc's stock price $97.23 by its total outstanding shares 62515666 (62.52 Million).

Protagonist Therapeutics Inc Market Cap History: 2016 to 2026

Protagonist Therapeutics Inc's market capitalization history from 2016 to 2026. Data shows growth from $1.37 Billion to $6.08 Billion (24.67% CAGR).

Index Memberships

Protagonist Therapeutics Inc is a constituent of 4 market indices:

Index Total Market Cap Weight (%) Rank by Market Cap
NASDAQ Health Care
IXHC
$2.24 Trillion 0.22% #62 of 976
NASDAQ Composite
IXIC
$33.39 Trillion 0.01% #349 of 3165
NASDAQ Biotechnology
NBI
$1.54 Trillion 0.31% #41 of 263
S&P Small-Cap 600 Index
SML
$1.36 Trillion 0.21% #58 of 602

Weight: Protagonist Therapeutics Inc's market cap as a percentage of total index value. Rank: Position among all constituents by market cap.

Protagonist Therapeutics Inc Market Cap to Earnings & Revenue Ratios Timeline

This chart shows how Protagonist Therapeutics Inc's valuation ratios have evolved. The Price to Sales (P/S) ratio compares market cap to revenue, while the Price to Earnings (P/E) ratio compares market cap to net income. Lower values may indicate a more undervalued company relative to its financial performance.

Latest Price to Sales (P/S) Ratio

5.55x

Protagonist Therapeutics Inc's market cap is 5.55 times its annual revenue

Industry average:
1728.56x
Lower than industry average

Latest Price to Earnings (P/E) Ratio

8.77x

Protagonist Therapeutics Inc's market cap is 8.77 times its annual earnings

Industry average:
0.11x
Higher than industry average
What These Ratios Tell Investors:
  • Price to Sales (P/S) Ratio: Shows how much investors are paying for each dollar of the company's sales. Lower P/S ratios may indicate undervaluation.
  • Price to Earnings (P/E) Ratio: Shows how much investors are paying for each dollar of the company's earnings. This is one of the most common valuation metrics.
  • Trends in these ratios over time can indicate changing investor sentiment about the company's future growth prospects.
  • Industry comparison provides context for whether the company is valued higher or lower than peers.
Year Market Cap (USD) Revenue (USD) Net Income (USD) P/S Ratio P/E Ratio
2017 $1.30 Billion $20.06 Million -$36.96 Million 64.81x N/A
2018 $420.73 Million $30.93 Million -$38.92 Million 13.60x N/A
2019 $440.74 Million $231.00K -$77.19 Million 1907.95x N/A
2020 $1.26 Billion $28.63 Million -$66.15 Million 44.02x N/A
2021 $2.14 Billion $27.36 Million -$125.55 Million 78.15x N/A
2022 $682.05 Million $26.58 Million -$123.41 Million 25.66x N/A
2023 $1.43 Billion $60.00 Million -$78.95 Million 23.89x N/A
2024 $2.41 Billion $434.43 Million $275.19 Million 5.55x 8.77x

Competitor Companies of PTGX by Market Capitalization

Companies near Protagonist Therapeutics Inc in the global market cap rankings as of March 19, 2026.

Key companies related to Protagonist Therapeutics Inc by market ranking:

  • Vertex Pharmaceuticals Inc (NASDAQ:VRTX): Ranked #162 globally with a market cap of $117.09 Billion USD.
  • Regeneron Pharmaceuticals Inc (NASDAQ:REGN): Ranked #281 globally with a market cap of $74.80 Billion USD.
  • CSL Limited (PINK:CMXHF): Ranked #344 globally with a market cap of $63.46 Billion USD.
  • argenx SE (OTCGREY:ARGNF): Ranked #500 globally with a market cap of $42.99 Billion USD.

Market capitalization comparison (in billions USD)
Rank Company Symbol Market Cap Price
#162 Vertex Pharmaceuticals Inc NASDAQ:VRTX $117.09 Billion $462.49
#281 Regeneron Pharmaceuticals Inc NASDAQ:REGN $74.80 Billion $759.05
#344 CSL Limited PINK:CMXHF $63.46 Billion $149.87
#500 argenx SE OTCGREY:ARGNF $42.99 Billion $697.42

Protagonist Therapeutics Inc Historical Marketcap From 2016 to 2026

Between 2016 and today, Protagonist Therapeutics Inc's market cap moved from $1.37 Billion to $ 6.08 Billion, with a yearly change of 24.67%.

Year Market Cap Change (%)
2026 $6.08 Billion +11.32%
2025 $5.46 Billion +126.27%
2024 $2.41 Billion +68.34%
2023 $1.43 Billion +110.17%
2022 $682.05 Million -68.10%
2021 $2.14 Billion +69.64%
2020 $1.26 Billion +185.96%
2019 $440.74 Million +4.75%
2018 $420.73 Million -67.64%
2017 $1.30 Billion -5.41%
2016 $1.37 Billion --

End of Day Market Cap According to Different Sources

On Mar 18th, 2026 the market cap of Protagonist Therapeutics Inc was reported to be:

Source Market Cap
Yahoo Finance $6.08 Billion USD
MoneyControl $6.08 Billion USD
MarketWatch $6.08 Billion USD
marketcap.company $6.08 Billion USD
Reuters $6.08 Billion USD

Market cap values may vary slightly between sources due to differences in calculation methods, timing, and data refresh rates.