Upstream Bio, Inc. (UPB) — Defensive Interval Ratio

Latest as of June 2026: 6726 days

Upstream Bio, Inc. (UPB) has a Defensive Interval Ratio of 6726 days as of June 2026. Defensive assets of $184.06 Million (cash $-, short-term investments $181.91 Million, receivables $2.15 Million) cover 6726 days of daily cash needs of $27.36K/day.

Defensive Interval Ratio

6726 days
Days of operational coverage

Defensive Assets

$184.06 Million
Cash + ST Investments + Receivables

Daily Cash Need

$27.36K
Current Liabilities ÷ 365

Current Liabilities

$9.99 Million
USD

Upstream Bio, Inc. Defensive Interval Ratio (2022–2025)

This chart shows how Upstream Bio, Inc.'s Defensive Interval Ratio has evolved across 4 annual periods from 2022 to 2025. As of June 2026, the ratio stands at 6726 days, meaning defensive assets of $184.06 Million can fund 6726 days of operations without new revenue. For the complete balance sheet picture, see Upstream Bio, Inc. balance sheet assets.

Annual Defensive Interval Ratio for Upstream Bio, Inc. (2022–2025)

The table below presents the year-by-year Defensive Interval Ratio for Upstream Bio, Inc. from 2022 to 2025, covering 4 annual filings. Each row shows defensive assets, daily cash need, the DIR in days, and the change in days compared to the prior year. See UPB net working capital ratio to evaluate short-term liquidity relative to the company's equity base.

Year DIR (days) Defensive Assets (USD) Daily Cash Need Cash ST Investments Change (days)
2025 6528 days $240.60 Million $36.85K/day $- $239.93 Million ▲ +1574 days
2024 4954 days $145.74 Million $29.42K/day $- $144.56 Million ▲ +236 days
2023 4718 days $84.21 Million $17.85K/day $- $83.98 Million ▲ +4687 days
2022 31 days $412.00K $13.30K/day $- $0.00
DIR = (Cash + Short-term Investments + Net Receivables) / (Daily Cash Expenses)