Spero Therapeutics Inc (SPRO) — Financial Flexibility Index

Latest as of December 2025: -0.84x

Spero Therapeutics Inc (SPRO) has a Financial Flexibility Index of -0.84x as of December 2025. Free cash flow of $-8.35 Million (operating CF $-8.35 Million minus capex $0.00) represents -1% of total liabilities ($9.90 Million). Check total reinvestment intensity of Spero Therapeutics Inc to assess the company's total reinvestment commitment from operating cash flow.

Financial Flexibility Index

-0.84x
Free Cash Flow / Total Liabilities

Free Cash Flow

$-8.35 Million
Operating CF − Capex

Total Liabilities

$9.90 Million
USD

Capital Expenditures

$0.00
USD

Spero Therapeutics Inc Financial Flexibility Index (2015–2025)

Historical Financial Flexibility Index trend for Spero Therapeutics Inc across 11 annual periods. For the full cash flow conversion analysis, see Spero Therapeutics Inc (SPRO) cash flow conversion.

Annual Financial Flexibility Index for Spero Therapeutics Inc (2015–2025)

Year-by-year free cash flow to debt coverage for Spero Therapeutics Inc. Explore cash flow to debt ratio of Spero Therapeutics Inc to assess how comfortably operating cash covers total debt obligations.

Year Flexibility Index Free Cash Flow (USD) Operating CF Total Liabilities YoY Change
2025 -1.28x $-12.62 Million $-12.62 Million $9.90 Million ▼ -250.5%
2024 -0.36x $-23.44 Million $-23.44 Million $64.42 Million ▲ +16.7%
2023 -0.44x $-32.99 Million $-32.99 Million $75.50 Million ▼ -176.3%
2022 -0.16x $-7.73 Million $-7.73 Million $48.87 Million
2021 0.00x $0.00 $-64.35 Million $82.78 Million ▲ +100.0%
2020 -4.00x $-85.72 Million $-85.87 Million $21.41 Million ▼ -153.9%
2019 -1.58x $-49.71 Million $-50.02 Million $31.53 Million ▲ +44.3%
2018 -2.83x $-37.19 Million $-39.62 Million $13.15 Million ▲ +38.3%
2017 -4.59x $-39.08 Million $-39.11 Million $8.52 Million ▼ -20.8%
2016 -3.80x $-28.13 Million $-28.96 Million $7.41 Million ▼ -200.9%
2015 -1.26x $-9.38 Million $-9.61 Million $7.43 Million
Financial Flexibility Index = (Operating CF − Capex) / Total Liabilities = Free Cash Flow / Total Liabilities