Denali Therapeutics Inc (NASDAQ:DNLI) — Market Cap & Net Worth

$3.30 Billion USD  · Rank #4750

Market Cap & Net Worth: Denali Therapeutics Inc (DNLI)

Denali Therapeutics Inc (NASDAQ:DNLI) has a market capitalization of $3.30 Billion ($3.30 Billion) as of June 18, 2026. Listed on the NASDAQ stock exchange, this USA-based company holds position #4750 globally and #1574 in its home market, demonstrating a 12.23% increase in market value over the past year.

Market capitalization, also known as net worth in stock markets, is calculated by multiplying Denali Therapeutics Inc's stock price $21.93 by its total outstanding shares 158709737 (158.71 Million). Review DNLI total liabilities to assess the company's total debt and financial obligations.

Denali Therapeutics Inc Market Cap History: 2017 to 2026

Denali Therapeutics Inc's market capitalization history from 2017 to 2026. Data shows growth from $2.48 Billion to $3.48 Billion (0.26% CAGR).

Index Memberships

Denali Therapeutics Inc is a constituent of 3 market indices:

Index Total Market Cap Weight (%) Rank by Market Cap
NASDAQ Health Care
IXHC
$2.43 Trillion 0.14% #114 of 976
NASDAQ Composite
IXIC
$41.27 Trillion 0.01% #533 of 3165
NASDAQ Biotechnology
NBI
$1.70 Trillion 0.19% #72 of 263

Weight: Denali Therapeutics Inc's market cap as a percentage of total index value. Rank: Position among all constituents by market cap.

Denali Therapeutics Inc Market Cap to Earnings & Revenue Ratios Timeline

This chart shows how Denali Therapeutics Inc's valuation ratios have evolved. The Price to Sales (P/S) ratio compares market cap to revenue, while the Price to Earnings (P/E) ratio compares market cap to net income. Lower values may indicate a more undervalued company relative to its financial performance.

Latest Price to Sales (P/S) Ratio

10.30x

Denali Therapeutics Inc's market cap is 10.30 times its annual revenue

Industry average: 7883.64x Lower than industry average

Latest Price to Earnings (P/E) Ratio

N/A

P/E ratio not applicable due to negative or zero earnings

What These Ratios Tell Investors:

  • Price to Sales (P/S) Ratio: Shows how much investors are paying for each dollar of the company's sales. Lower P/S ratios may indicate undervaluation.
  • Price to Earnings (P/E) Ratio: Shows how much investors are paying for each dollar of the company's earnings. This is one of the most common valuation metrics.
  • Trends in these ratios over time can indicate changing investor sentiment about the company's future growth prospects.
  • Industry comparison provides context for whether the company is valued higher or lower than peers.
Year Market Cap (USD) Revenue (USD) Net Income (USD) P/S Ratio P/E Ratio
2018 $3.28 Billion $129.16 Million -$36.24 Million 25.39x N/A
2019 $2.76 Billion $26.68 Million -$197.61 Million 103.63x N/A
2020 $13.29 Billion $335.66 Million $71.14 Million 39.60x 186.87x
2021 $7.08 Billion $48.66 Million -$290.58 Million 145.46x N/A
2022 $4.41 Billion $108.46 Million -$325.99 Million 40.69x N/A
2023 $3.41 Billion $330.53 Million -$145.22 Million 10.30x N/A

Competitor Companies of DNLI by Market Capitalization

Companies near Denali Therapeutics Inc in the global market cap rankings as of June 18, 2026.

Key companies related to Denali Therapeutics Inc by market ranking:

  • Vertex Pharmaceuticals Inc (NASDAQ:VRTX): Ranked #222 globally with a market cap of $110.45 Billion USD.
  • Regeneron Pharmaceuticals Inc (NASDAQ:REGN): Ranked #442 globally with a market cap of $63.33 Billion USD.
  • UCB SA (BR:UCB): Ranked #550 globally with a market cap of $49.68 Billion USD ( €42.50 Billion EUR).
  • Argen-X (BR:ARGX): Ranked #574 globally with a market cap of $47.14 Billion USD ( €40.32 Billion EUR).
Market capitalization comparison (in billions USD)
Rank Company Symbol Market Cap Price
#222 Vertex Pharmaceuticals Inc NASDAQ:VRTX $110.45 Billion $453.17
#442 Regeneron Pharmaceuticals Inc NASDAQ:REGN $63.33 Billion $614.73
#550 UCB SA BR:UCB $49.68 Billion €250.00
#574 Argen-X BR:ARGX $47.14 Billion €755.80

Denali Therapeutics Inc Historical Marketcap From 2017 to 2026

Between 2017 and today, Denali Therapeutics Inc's market cap moved from $2.48 Billion to $ 3.48 Billion, with a yearly change of 0.26%.

Year Market Cap Change (%)
2026 $3.48 Billion +32.83%
2025 $2.62 Billion -18.99%
2024 $3.23 Billion -5.03%
2023 $3.41 Billion -22.83%
2022 $4.41 Billion -37.65%
2021 $7.08 Billion -46.75%
2020 $13.29 Billion +380.83%
2019 $2.76 Billion -15.68%
2018 $3.28 Billion +32.10%
2017 $2.48 Billion --

End of Day Market Cap According to Different Sources

On Jun 17th, 2026 the market cap of Denali Therapeutics Inc was reported to be:

Source Market Cap
Yahoo Finance $3.30 Billion USD
MoneyControl $3.30 Billion USD
MarketWatch $3.30 Billion USD
marketcap.company $3.30 Billion USD
Reuters $3.30 Billion USD

Market cap values may vary slightly between sources due to differences in calculation methods, timing, and data refresh rates.

About Denali Therapeutics Inc

NASDAQ:DNLI USA Biotechnology
Market Cap
$3.48 Billion
Market Cap Rank
#4750 Global
#1574 in USA
Share Price
$21.93
Change (1 day)
-1.31%
52-Week Range
$12.75 - $22.74
All Time High
$93.56
About

Denali Therapeutics Inc., a biopharmaceutical company, discovers and develops therapeutics to treat neurodegenerative and lysosomal storage diseases. The company develops Eclitasertib (SAR443122/DNL758) RIPK1 inhibitor program for peripheral inflammatory diseases; BIIB122/DNL151 LRRK2 inhibitor program for Parkinson's disease; TAK-594/DNL593 program for frontotemporal dementia-granulin; DNL126 pr… Read more