Orchestra BioMed Holdings Inc. (NASDAQ:OBIO) — Market Cap & Net Worth

$327.57 Million USD  · Rank #14526

Market Cap & Net Worth: Orchestra BioMed Holdings Inc. (OBIO)

Orchestra BioMed Holdings Inc. (NASDAQ:OBIO) has a market capitalization of $327.57 Million ($327.57 Million) as of September 25, 2026. Listed on the NASDAQ stock exchange, this USA-based company holds position #14526 globally and #3432 in its home market, demonstrating a -1.00% decrease in market value over the past year.

Market capitalization, also known as net worth in stock markets, is calculated by multiplying Orchestra BioMed Holdings Inc.'s stock price $5.95 by its total outstanding shares 60105049 (60.11 Million). Also see Orchestra BioMed Holdings Inc. balance sheet assets for a full breakdown of the balance sheet.

Orchestra BioMed Holdings Inc. Market Cap History: 2020 to 2026

Orchestra BioMed Holdings Inc.'s market capitalization history from 2020 to 2026. Data shows change from $769.95 Million to $357.63 Million (-10.04% CAGR). Also see Orchestra BioMed Holdings Inc. operating cash flow efficiency for how efficiently the company converts equity into cash flow.

Index Memberships

Orchestra BioMed Holdings Inc. is a constituent of 2 market indices:

Index Total Market Cap Weight (%) Rank by Market Cap
NASDAQ Health Care
IXHC
$2.64 Trillion 0.01% #390 of 976
NASDAQ Composite
IXIC
$42.16 Trillion 0.00% #1404 of 3165

Weight: Orchestra BioMed Holdings Inc.'s market cap as a percentage of total index value. Rank: Position among all constituents by market cap.

Orchestra BioMed Holdings Inc. Market Cap to Earnings & Revenue Ratios Timeline

This chart shows how Orchestra BioMed Holdings Inc.'s valuation ratios have evolved. The Price to Sales (P/S) ratio compares market cap to revenue, while the Price to Earnings (P/E) ratio compares market cap to net income. Lower values may indicate a more undervalued company relative to its financial performance. Check OBIO stock price for real-time trading data and today's change.

Latest Price to Sales (P/S) Ratio

7.45x

Orchestra BioMed Holdings Inc.'s market cap is 7.45 times its annual revenue

Industry average: 3904.65x Lower than industry average

Latest Price to Earnings (P/E) Ratio

N/A

P/E ratio not applicable due to negative or zero earnings

What These Ratios Tell Investors:

  • Price to Sales (P/S) Ratio: Shows how much investors are paying for each dollar of the company's sales. Lower P/S ratios may indicate undervaluation.
  • Price to Earnings (P/E) Ratio: Shows how much investors are paying for each dollar of the company's earnings. This is one of the most common valuation metrics.
  • Trends in these ratios over time can indicate changing investor sentiment about the company's future growth prospects.
  • Industry comparison provides context for whether the company is valued higher or lower than peers.
Year Market Cap (USD) Revenue (USD) Net Income (USD) P/S Ratio P/E Ratio
2020 $769.95 Million $5.70 Million -$21.36 Million 135.01x N/A
2021 $605.86 Million $-782.00K -$23.01 Million -774.76x N/A
2022 $599.85 Million $3.53 Million -$33.61 Million 169.78x N/A
2023 $548.76 Million $2.76 Million -$49.12 Million 198.83x N/A
2024 $252.44 Million $2.64 Million -$61.02 Million 95.69x N/A
2025 $249.44 Million $33.48 Million -$52.70 Million 7.45x N/A

Competitor Companies of OBIO by Market Capitalization

Companies near Orchestra BioMed Holdings Inc. in the global market cap rankings as of September 25, 2026. Review OBIO goodwill-adjusted equity ratio to assess the quality of the company's equity after excluding intangible assets.

Key companies related to Orchestra BioMed Holdings Inc. by market ranking:

  • Vertex Pharmaceuticals Inc (NASDAQ:VRTX): Ranked #186 globally with a market cap of $130.90 Billion USD.
  • Regeneron Pharmaceuticals Inc (NASDAQ:REGN): Ranked #333 globally with a market cap of $80.46 Billion USD.
  • CSL Ltd (AU:CSL): Ranked #450 globally with a market cap of $61.49 Billion USD ( AU$86.90 Billion AUD).
  • Moderna Inc (NASDAQ:MRNA): Ranked #506 globally with a market cap of $54.14 Billion USD.
Market capitalization comparison (in billions USD)
Rank Company Symbol Market Cap Price
#186 Vertex Pharmaceuticals Inc NASDAQ:VRTX $130.90 Billion $522.38
#333 Regeneron Pharmaceuticals Inc NASDAQ:REGN $80.46 Billion $796.02
#450 CSL Ltd AU:CSL $61.49 Billion AU$179.12
#506 Moderna Inc NASDAQ:MRNA $54.14 Billion $194.82

Orchestra BioMed Holdings Inc. Historical Marketcap From 2020 to 2026

Between 2020 and today, Orchestra BioMed Holdings Inc.'s market cap moved from $769.95 Million to $ 357.63 Million, with a yearly change of -10.04%.

Year Market Cap Change (%)
2026 $357.63 Million +43.37%
2025 $249.44 Million -1.19%
2024 $252.44 Million -54.00%
2023 $548.76 Million -8.52%
2022 $599.85 Million -0.99%
2021 $605.86 Million -21.31%
2020 $769.95 Million --

End of Day Market Cap According to Different Sources

On Sep 25th, 2026 the market cap of Orchestra BioMed Holdings Inc. was reported to be:

Source Market Cap
Yahoo Finance $327.57 Million USD
MoneyControl $327.57 Million USD
MarketWatch $327.57 Million USD
marketcap.company $327.57 Million USD
Reuters $327.57 Million USD

Market cap values may vary slightly between sources due to differences in calculation methods, timing, and data refresh rates.

About Orchestra BioMed Holdings Inc.

NASDAQ:OBIO USA Biotechnology
Market Cap
$357.63 Million
Market Cap Rank
#14526 Global
#3432 in USA
Share Price
$5.95
Change (1 day)
+0.34%
52-Week Range
$2.42 - $6.25
All Time High
$22.18
About

Orchestra BioMed Holdings, Inc. operates as a biomedical company in the United States. The company's flagship product candidates include Atrioventricular Interval Modulation, a bioelectronic therapy candidate designed to immediately, substantially, and persistently lower blood pressure; and Virtue Sirolimus AngioInfusion Balloon for the treatment of atherosclerotic artery disease. It also develop… Read more