Septerna, Inc. Common Stock (NASDAQ:SEPN) — Market Cap & Net Worth

$1.64 Billion USD  · Rank #6904

Market Cap & Net Worth: Septerna, Inc. Common Stock (SEPN)

Septerna, Inc. Common Stock (NASDAQ:SEPN) has a market capitalization of $1.64 Billion ($1.64 Billion) as of September 17, 2026. Listed on the NASDAQ stock exchange, this USA-based company holds position #6904 globally and #2141 in its home market, demonstrating a 2.86% increase in market value over the past year.

Market capitalization, also known as net worth in stock markets, is calculated by multiplying Septerna, Inc. Common Stock's stock price $38.44 by its total outstanding shares 45075533 (45.08 Million). Also see SEPN total asset value for a full breakdown of the balance sheet.

Septerna, Inc. Common Stock Market Cap History: 2024 to 2026

Septerna, Inc. Common Stock's market capitalization history from 2024 to 2026. Data shows growth from $1.03 Billion to $1.73 Billion (49.21% CAGR). Also see SEPN operating cash flow for how efficiently the company converts equity into cash flow.

Index Memberships

Septerna, Inc. Common Stock is a constituent of 2 market indices:

Index Total Market Cap Weight (%) Rank by Market Cap
NASDAQ Health Care
IXHC
$2.66 Trillion 0.06% #200 of 976
NASDAQ Composite
IXIC
$41.69 Trillion 0.00% #780 of 3165

Weight: Septerna, Inc. Common Stock's market cap as a percentage of total index value. Rank: Position among all constituents by market cap.

Septerna, Inc. Common Stock Market Cap to Earnings & Revenue Ratios Timeline

This chart shows how Septerna, Inc. Common Stock's valuation ratios have evolved. The Price to Sales (P/S) ratio compares market cap to revenue, while the Price to Earnings (P/E) ratio compares market cap to net income. Lower values may indicate a more undervalued company relative to its financial performance. Check latest Septerna, Inc. Common Stock stock price today for real-time trading data and today's change.

Latest Price to Sales (P/S) Ratio

27.35x

Septerna, Inc. Common Stock's market cap is 27.35 times its annual revenue

Industry average: 3887.01x Lower than industry average

Latest Price to Earnings (P/E) Ratio

N/A

P/E ratio not applicable due to negative or zero earnings

What These Ratios Tell Investors:

  • Price to Sales (P/S) Ratio: Shows how much investors are paying for each dollar of the company's sales. Lower P/S ratios may indicate undervaluation.
  • Price to Earnings (P/E) Ratio: Shows how much investors are paying for each dollar of the company's earnings. This is one of the most common valuation metrics.
  • Trends in these ratios over time can indicate changing investor sentiment about the company's future growth prospects.
  • Industry comparison provides context for whether the company is valued higher or lower than peers.
Year Market Cap (USD) Revenue (USD) Net Income (USD) P/S Ratio P/E Ratio
2024 $1.03 Billion $1.07 Million -$71.80 Million 960.21x N/A
2025 $1.26 Billion $45.95 Million -$48.88 Million 27.35x N/A

Competitor Companies of SEPN by Market Capitalization

Companies near Septerna, Inc. Common Stock in the global market cap rankings as of September 17, 2026. Review SEPN tangible net worth ratio to assess the quality of the company's equity after excluding intangible assets.

Key companies related to Septerna, Inc. Common Stock by market ranking:

  • Vertex Pharmaceuticals Inc (NASDAQ:VRTX): Ranked #187 globally with a market cap of $130.09 Billion USD.
  • Regeneron Pharmaceuticals Inc (NASDAQ:REGN): Ranked #353 globally with a market cap of $78.34 Billion USD.
  • CSL Ltd (AU:CSL): Ranked #457 globally with a market cap of $59.87 Billion USD ( AU$84.62 Billion AUD).
  • Moderna Inc (NASDAQ:MRNA): Ranked #505 globally with a market cap of $54.14 Billion USD.
Market capitalization comparison (in billions USD)
Rank Company Symbol Market Cap Price
#187 Vertex Pharmaceuticals Inc NASDAQ:VRTX $130.09 Billion $513.26
#353 Regeneron Pharmaceuticals Inc NASDAQ:REGN $78.34 Billion $774.61
#457 CSL Ltd AU:CSL $59.87 Billion AU$174.41
#505 Moderna Inc NASDAQ:MRNA $54.14 Billion $145.62

Septerna, Inc. Common Stock Historical Marketcap From 2024 to 2026

Between 2024 and today, Septerna, Inc. Common Stock's market cap moved from $1.03 Billion to $ 1.73 Billion, with a yearly change of 49.21%.

Year Market Cap Change (%)
2026 $1.73 Billion +37.88%
2025 $1.26 Billion +21.75%
2024 $1.03 Billion --

End of Day Market Cap According to Different Sources

On Sep 17th, 2026 the market cap of Septerna, Inc. Common Stock was reported to be:

Source Market Cap
Yahoo Finance $1.64 Billion USD
MoneyControl $1.64 Billion USD
MarketWatch $1.64 Billion USD
marketcap.company $1.64 Billion USD
Reuters $1.64 Billion USD

Market cap values may vary slightly between sources due to differences in calculation methods, timing, and data refresh rates.

About Septerna, Inc. Common Stock

NASDAQ:SEPN USA Biotechnology
Market Cap
$1.73 Billion
Market Cap Rank
#6904 Global
#2141 in USA
Share Price
$38.44
Change (1 day)
-1.08%
52-Week Range
$15.70 - $48.19
All Time High
$48.19
About

Septerna, Inc., a clinical-stage biotechnology company, discovers and develops G protein-coupled receptor (GPCR) oral small molecule products for the treatment of endocrinology, immunology and inflammation, and metabolic diseases. It develops PTH1R Program, oral small molecule Parathyroid Hormone 1 Receptor agonists for the treatment of hypoparathyroidism; SEP-631, an oral small molecule MRGPRX2 … Read more