Sionna Therapeutics, Inc. Common Stock (NASDAQ:SION) — Market Cap & Net Worth

$316.79 Million USD  · Rank #14621

Market Cap & Net Worth: Sionna Therapeutics, Inc. Common Stock (SION)

Sionna Therapeutics, Inc. Common Stock (NASDAQ:SION) has a market capitalization of $316.79 Million ($316.79 Million) as of September 17, 2026. Listed on the NASDAQ stock exchange, this USA-based company holds position #14621 globally and #3467 in its home market, demonstrating a -3.56% decrease in market value over the past year.

Market capitalization, also known as net worth in stock markets, is calculated by multiplying Sionna Therapeutics, Inc. Common Stock's stock price $7.04 by its total outstanding shares 44998073 (45.00 Million). Also see Sionna Therapeutics, Inc. Common Stock assets under control for a full breakdown of the balance sheet.

Sionna Therapeutics, Inc. Common Stock Market Cap History: 2025 to 2026

Sionna Therapeutics, Inc. Common Stock's market capitalization history from 2025 to 2026. Data shows change from $1.85 Billion to $316.79 Million (-54.59% CAGR). Also see SION cash generation efficiency for how efficiently the company converts equity into cash flow.

Index Memberships

Sionna Therapeutics, Inc. Common Stock is a constituent of 1 market index:

Index Total Market Cap Weight (%) Rank by Market Cap
NASDAQ Health Care
IXHC
$2.66 Trillion 0.01% #398 of 976

Weight: Sionna Therapeutics, Inc. Common Stock's market cap as a percentage of total index value. Rank: Position among all constituents by market cap.

Sionna Therapeutics, Inc. Common Stock Market Cap to Earnings & Revenue Ratios Timeline

This chart shows how Sionna Therapeutics, Inc. Common Stock's valuation ratios have evolved. The Price to Sales (P/S) ratio compares market cap to revenue, while the Price to Earnings (P/E) ratio compares market cap to net income. Lower values may indicate a more undervalued company relative to its financial performance. Check latest Sionna Therapeutics, Inc. Common Stock stock price today for real-time trading data and today's change.

Latest Price to Sales (P/S) Ratio

No P/S ratio data available

Latest Price to Earnings (P/E) Ratio

No P/E ratio data available

What These Ratios Tell Investors:

  • Price to Sales (P/S) Ratio: Shows how much investors are paying for each dollar of the company's sales. Lower P/S ratios may indicate undervaluation.
  • Price to Earnings (P/E) Ratio: Shows how much investors are paying for each dollar of the company's earnings. This is one of the most common valuation metrics.
  • Trends in these ratios over time can indicate changing investor sentiment about the company's future growth prospects.
  • Industry comparison provides context for whether the company is valued higher or lower than peers.
Year Market Cap (USD) Revenue (USD) Net Income (USD) P/S Ratio P/E Ratio
No financial ratio data available

Competitor Companies of SION by Market Capitalization

Companies near Sionna Therapeutics, Inc. Common Stock in the global market cap rankings as of September 17, 2026. Review SION intangible-adjusted equity ratio to assess the quality of the company's equity after excluding intangible assets.

Key companies related to Sionna Therapeutics, Inc. Common Stock by market ranking:

  • Vertex Pharmaceuticals Inc (NASDAQ:VRTX): Ranked #187 globally with a market cap of $130.09 Billion USD.
  • Regeneron Pharmaceuticals Inc (NASDAQ:REGN): Ranked #353 globally with a market cap of $78.34 Billion USD.
  • CSL Ltd (AU:CSL): Ranked #457 globally with a market cap of $59.87 Billion USD ( AU$84.62 Billion AUD).
  • Moderna Inc (NASDAQ:MRNA): Ranked #505 globally with a market cap of $54.14 Billion USD.
Market capitalization comparison (in billions USD)
Rank Company Symbol Market Cap Price
#187 Vertex Pharmaceuticals Inc NASDAQ:VRTX $130.09 Billion $513.26
#353 Regeneron Pharmaceuticals Inc NASDAQ:REGN $78.34 Billion $774.61
#457 CSL Ltd AU:CSL $59.87 Billion AU$174.41
#505 Moderna Inc NASDAQ:MRNA $54.14 Billion $145.62

Sionna Therapeutics, Inc. Common Stock Historical Marketcap From 2025 to 2026

Between 2025 and today, Sionna Therapeutics, Inc. Common Stock's market cap moved from $1.85 Billion to $ 316.79 Million, with a yearly change of -54.59%.

Year Market Cap Change (%)
2026 $316.79 Million -82.89%
2025 $1.85 Billion --

End of Day Market Cap According to Different Sources

On Sep 17th, 2026 the market cap of Sionna Therapeutics, Inc. Common Stock was reported to be:

Source Market Cap
Yahoo Finance $316.79 Million USD
MoneyControl $316.79 Million USD
MarketWatch $316.79 Million USD
marketcap.company $316.79 Million USD
Reuters $316.79 Million USD

Market cap values may vary slightly between sources due to differences in calculation methods, timing, and data refresh rates.

About Sionna Therapeutics, Inc. Common Stock

NASDAQ:SION USA Biotechnology
Market Cap
$316.79 Million
Market Cap Rank
#14621 Global
#3467 in USA
Share Price
$7.04
Change (1 day)
+2.33%
52-Week Range
$4.50 - $51.04
All Time High
$51.04
About

Sionna Therapeutics, Inc., a clinical-stage biopharmaceutical company, researches and develops medicines for the treatment of cystic fibrosis (CF). It develops galicaftor (SION-2222), a transmembrane domain 1 (TMD1)-directed cystic fibrosis transmembrane conductance regulator (CFTR) that has completed Phase 2 trial; navocaftor (SION-3067), a potentiator that has completed Phase 2 trial; SION-109,… Read more