Ionis Pharmaceuticals Inc Cash Flow-to-Debt Ratio
Ionis Pharmaceuticals Inc cash flow-to-debt ratio. Ionis Pharmaceuticals Inc (IONS) has a Cash Flow-to-Debt Ratio of 0.22x as of June 2026, meaning its operating cash flow of $565.53 Million could theoretically repay 0% of its total liabilities ($2.56 Billion) in one year. Check Ionis Pharmaceuticals Inc cash flow quality index to evaluate the quality of earnings relative to operating cash generation.
CF-to-Debt Ratio
Operating Cash Flow
Total Liabilities
Data as of
Cash Flow-to-Debt Ratio of Ionis Pharmaceuticals Inc (1991–2025)
Cash flow-to-debt ratio of Ionis Pharmaceuticals Inc from 1991 to 2025. Historical debt coverage capacity for Ionis Pharmaceuticals Inc across 35 annual periods. Check IONS capex plus investments ratio to assess the company's total reinvestment commitment from operating cash flow.
Ionis Pharmaceuticals Inc Cash Flow-to-Debt Ratio by Year (1991–2025)
Ionis Pharmaceuticals Inc cash flow-to-debt ratio by year from 1991 to 2025. Year-by-year debt coverage analysis for Ionis Pharmaceuticals Inc. For the full cash flow conversion analysis, see IONS cash flow conversion.
| Year | CF-to-Debt Ratio | Operating CF (USD) | Total Liabilities | YoY Change |
|---|---|---|---|---|
| 2025 | -0.09x | $-268.58 Million | $3.03 Billion | ▲ +57.3% |
| 2024 | -0.21x | $-500.95 Million | $2.42 Billion | ▼ -75.6% |
| 2023 | -0.12x | $-307.51 Million | $2.60 Billion | ▲ +15.6% |
| 2022 | -0.14x | $-274.37 Million | $1.96 Billion | ▼ -935.9% |
| 2021 | 0.02x | $30.80 Million | $1.84 Billion | ▼ -27.9% |
| 2020 | 0.02x | $35.89 Million | $1.55 Billion | ▼ -89.6% |
| 2019 | 0.22x | $345.72 Million | $1.55 Billion | ▼ -45.2% |
| 2018 | 0.41x | $602.89 Million | $1.48 Billion | ▲ +111.2% |
| 2017 | 0.19x | $174.15 Million | $903.30 Million | ▲ +239.8% |
| 2016 | -0.14x | $-112.11 Million | $812.90 Million | ▼ -593.1% |
| 2015 | 0.03x | $21.12 Million | $755.32 Million | ▲ +210.6% |
| 2014 | 0.01x | $6.29 Million | $698.03 Million | ▼ -93.4% |
| 2013 | 0.14x | $63.49 Million | $468.77 Million | ▲ +2520.3% |
| 2012 | 0.01x | $1.88 Million | $362.92 Million | ▲ +101.4% |
| 2011 | -0.37x | $-114.80 Million | $313.46 Million | ▼ -76.2% |
| 2010 | -0.21x | $-63.59 Million | $305.94 Million | ▲ +31.9% |
| 2009 | -0.31x | $-108.44 Million | $355.12 Million | ▼ -167.7% |
| 2008 | 0.45x | $212.03 Million | $469.90 Million | ▲ +210.8% |
| 2007 | 0.15x | $36.09 Million | $248.62 Million | ▲ +143.1% |
| 2006 | -0.34x | $-53.23 Million | $158.00 Million | ▲ +10.7% |
| 2005 | -0.38x | $-61.74 Million | $163.71 Million | ▼ -4.0% |
| 2004 | -0.36x | $-101.75 Million | $280.56 Million | ▼ -1.7% |
| 2003 | -0.36x | $-95.47 Million | $267.76 Million | ▼ -7.0% |
| 2002 | -0.33x | $-94.38 Million | $283.21 Million | ▼ -949.7% |
| 2001 | -0.03x | $-6.16 Million | $193.96 Million | ▲ +84.0% |
| 2000 | -0.20x | $-23.19 Million | $116.89 Million | ▲ +58.1% |
| 1999 | -0.47x | $-48.40 Million | $102.31 Million | ▼ -36.7% |
| 1998 | -0.35x | $-34.70 Million | $100.30 Million | ▼ -39.4% |
| 1997 | -0.25x | $-20.60 Million | $83.00 Million | ▲ +49.8% |
| 1996 | -0.49x | $-21.20 Million | $42.90 Million | ▲ +22.4% |
| 1995 | -0.64x | $-15.10 Million | $23.70 Million | ▲ +13.7% |
| 1994 | -0.74x | $-15.20 Million | $20.60 Million | ▲ +2.1% |
| 1993 | -0.75x | $-15.30 Million | $20.30 Million | ▲ +39.0% |
| 1992 | -1.24x | $-19.40 Million | $15.70 Million | ▼ -1094.5% |
| 1991 | -0.10x | $-1.50 Million | $14.50 Million | — |