Ionis Pharmaceuticals Inc (NASDAQ:IONS) — Market Cap & Net Worth

$7.85 Billion USD  · Rank #2664

Market Cap & Net Worth: Ionis Pharmaceuticals Inc (IONS)

Ionis Pharmaceuticals Inc (NASDAQ:IONS) has a market capitalization of $7.85 Billion ($7.85 Billion) as of September 16, 2026. Listed on the NASDAQ stock exchange, this USA-based company holds position #2664 globally and #968 in its home market, demonstrating a -18.66% decrease in market value over the past year.

Market capitalization, also known as net worth in stock markets, is calculated by multiplying Ionis Pharmaceuticals Inc's stock price $47.25 by its total outstanding shares 166184322 (166.18 Million). Also see Ionis Pharmaceuticals Inc assets under control for a full breakdown of the balance sheet.

Ionis Pharmaceuticals Inc Market Cap History: 2015 to 2026

Ionis Pharmaceuticals Inc's market capitalization history from 2015 to 2026. Data shows growth from $10.29 Billion to $7.85 Billion (0.63% CAGR). Also see IONS cash generation efficiency for how efficiently the company converts equity into cash flow.

Index Memberships

Ionis Pharmaceuticals Inc is a constituent of 4 market indices:

Index Total Market Cap Weight (%) Rank by Market Cap
Dow Jones Biotechnology
DJUSBT
$1.16 Trillion 0.68% #16 of 39
NASDAQ Health Care
IXHC
$2.66 Trillion 0.30% #65 of 976
NASDAQ Composite
IXIC
$41.74 Trillion 0.02% #308 of 3165
NASDAQ Biotechnology
NBI
$1.88 Trillion 0.42% #45 of 263

Weight: Ionis Pharmaceuticals Inc's market cap as a percentage of total index value. Rank: Position among all constituents by market cap.

Ionis Pharmaceuticals Inc Market Cap to Earnings & Revenue Ratios Timeline

This chart shows how Ionis Pharmaceuticals Inc's valuation ratios have evolved. The Price to Sales (P/S) ratio compares market cap to revenue, while the Price to Earnings (P/E) ratio compares market cap to net income. Lower values may indicate a more undervalued company relative to its financial performance. Check Ionis Pharmaceuticals Inc share price for real-time trading data and today's change.

Latest Price to Sales (P/S) Ratio

13.93x

Ionis Pharmaceuticals Inc's market cap is 13.93 times its annual revenue

Industry average: 3887.03x Lower than industry average

Latest Price to Earnings (P/E) Ratio

N/A

P/E ratio not applicable due to negative or zero earnings

What These Ratios Tell Investors:

  • Price to Sales (P/S) Ratio: Shows how much investors are paying for each dollar of the company's sales. Lower P/S ratios may indicate undervaluation.
  • Price to Earnings (P/E) Ratio: Shows how much investors are paying for each dollar of the company's earnings. This is one of the most common valuation metrics.
  • Trends in these ratios over time can indicate changing investor sentiment about the company's future growth prospects.
  • Industry comparison provides context for whether the company is valued higher or lower than peers.
Year Market Cap (USD) Revenue (USD) Net Income (USD) P/S Ratio P/E Ratio
2016 $7.95 Billion $346.62 Million -$86.56 Million 22.93x N/A
2017 $8.36 Billion $514.18 Million $346.00K 16.26x 24159.17x
2018 $8.98 Billion $599.67 Million $273.74 Million 14.98x 32.82x
2019 $10.04 Billion $1.12 Billion $294.00 Million 8.94x 34.15x
2020 $9.40 Billion $729.00 Million -$487.00 Million 12.89x N/A
2021 $5.06 Billion $810.46 Million -$28.60 Million 6.24x N/A
2022 $6.28 Billion $587.37 Million -$269.72 Million 10.69x N/A
2023 $8.41 Billion $787.65 Million -$366.29 Million 10.67x N/A
2024 $5.81 Billion $705.14 Million -$453.90 Million 8.24x N/A
2025 $13.15 Billion $944.00 Million -$381.00 Million 13.93x N/A

Competitor Companies of IONS by Market Capitalization

Companies near Ionis Pharmaceuticals Inc in the global market cap rankings as of September 16, 2026. Review tangible equity quality of Ionis Pharmaceuticals Inc to assess the quality of the company's equity after excluding intangible assets.

Key companies related to Ionis Pharmaceuticals Inc by market ranking:

  • Vertex Pharmaceuticals Inc (NASDAQ:VRTX): Ranked #186 globally with a market cap of $130.44 Billion USD.
  • Regeneron Pharmaceuticals Inc (NASDAQ:REGN): Ranked #353 globally with a market cap of $78.29 Billion USD.
  • CSL Ltd (AU:CSL): Ranked #457 globally with a market cap of $59.82 Billion USD ( AU$84.54 Billion AUD).
  • Moderna Inc (NASDAQ:MRNA): Ranked #506 globally with a market cap of $54.14 Billion USD.
Market capitalization comparison (in billions USD)
Rank Company Symbol Market Cap Price
#186 Vertex Pharmaceuticals Inc NASDAQ:VRTX $130.44 Billion $514.63
#353 Regeneron Pharmaceuticals Inc NASDAQ:REGN $78.29 Billion $774.11
#457 CSL Ltd AU:CSL $59.82 Billion AU$174.26
#506 Moderna Inc NASDAQ:MRNA $54.14 Billion $143.77

Ionis Pharmaceuticals Inc Historical Marketcap From 2015 to 2026

Between 2015 and today, Ionis Pharmaceuticals Inc's market cap moved from $10.29 Billion to $ 7.85 Billion, with a yearly change of 0.63%.

Year Market Cap Change (%)
2026 $7.85 Billion -40.27%
2025 $13.15 Billion +126.29%
2024 $5.81 Billion -30.90%
2023 $8.41 Billion +33.94%
2022 $6.28 Billion +24.12%
2021 $5.06 Billion -46.18%
2020 $9.40 Billion -6.41%
2019 $10.04 Billion +11.75%
2018 $8.98 Billion +7.48%
2017 $8.36 Billion +5.16%
2016 $7.95 Billion -22.77%
2015 $10.29 Billion --

End of Day Market Cap According to Different Sources

On Sep 16th, 2026 the market cap of Ionis Pharmaceuticals Inc was reported to be:

Source Market Cap
Yahoo Finance $7.85 Billion USD
MoneyControl $7.85 Billion USD
MarketWatch $7.85 Billion USD
marketcap.company $7.85 Billion USD
Reuters $7.85 Billion USD

Market cap values may vary slightly between sources due to differences in calculation methods, timing, and data refresh rates.

About Ionis Pharmaceuticals Inc

NASDAQ:IONS USA Biotechnology
Market Cap
$7.85 Billion
Market Cap Rank
#2664 Global
#968 in USA
Share Price
$47.25
Change (1 day)
-8.15%
52-Week Range
$47.25 - $86.50
All Time High
$86.50
About

Ionis Pharmaceuticals, Inc., a commercial-stage biotechnology company, provides RNA-targeted medicines in the United States. The company offers TRYNGOLZA reduces triglyceride levels in adults with familial chylomicronemia syndrome (FCS) and acute pancreatitis; DAWNZERA for prophylaxis to prevent attacks of hereditary angioedema in adults; WAINUA for the treatment of the polyneuropathy of heredita… Read more