Silence Therapeutics PLC Market Cap ($842.19 Million)

$842.19 Million USD  · Rank #9277

Market Cap & Net Worth: Silence Therapeutics PLC (SLN)

Silence Therapeutics PLC market cap. Silence Therapeutics PLC (NASDAQ:SLN) has a market capitalization of $842.19 Million ($842.19 Million) as of November 1, 2026. Listed on the NASDAQ stock exchange, this USA-based company holds position #9277 globally and #2631 in its home market, demonstrating a 0.46% increase in market value over the past year.

Market capitalization, also known as net worth in stock markets, is calculated by multiplying Silence Therapeutics PLC's stock price $19.75 by its total outstanding shares 62154086 (62.15 Million). Also see Silence Therapeutics PLC cash conversion from operations for how efficiently the company converts equity into cash flow.

Silence Therapeutics PLC Market Cap History (2020–2026)

Silence Therapeutics PLC market cap history from 2020 to 2026. Data shows growth from $1.37 Billion to $1.23 Billion (0.21% CAGR). Check SLN share price today for real-time trading data and today's change.

Index Memberships

Silence Therapeutics PLC is a constituent of 3 market indices:

Index Total Market Cap Weight (%) Rank by Market Cap
NASDAQ Health Care
IXHC
$2.62 Trillion 0.03% #269 of 976
NASDAQ Composite
IXIC
$40.09 Trillion 0.00% #997 of 3165
NASDAQ Biotechnology
NBI
$1.84 Trillion 0.05% #157 of 263

Weight: Silence Therapeutics PLC's market cap as a percentage of total index value. Rank: Position among all constituents by market cap.

Silence Therapeutics PLC Market Cap to Earnings & Revenue Ratios Timeline

This chart shows how Silence Therapeutics PLC's valuation ratios have evolved. The Price to Sales (P/S) ratio compares market cap to revenue, while the Price to Earnings (P/E) ratio compares market cap to net income. Lower values may indicate a more undervalued company relative to its financial performance. Explore SLN net asset momentum to track how rapidly the company is growing its equity base year over year.

Latest Price to Sales (P/S) Ratio

676.02x

Silence Therapeutics PLC's market cap is 676.02 times its annual revenue

Industry average: 3868.91x Lower than industry average

Latest Price to Earnings (P/E) Ratio

N/A

P/E ratio not applicable due to negative or zero earnings

What These Ratios Tell Investors:

  • Price to Sales (P/S) Ratio: Shows how much investors are paying for each dollar of the company's sales. Lower P/S ratios may indicate undervaluation.
  • Price to Earnings (P/E) Ratio: Shows how much investors are paying for each dollar of the company's earnings. This is one of the most common valuation metrics.
  • Trends in these ratios over time can indicate changing investor sentiment about the company's future growth prospects.
  • Industry comparison provides context for whether the company is valued higher or lower than peers.
Year Market Cap (USD) Revenue (USD) Net Income (USD) P/S Ratio P/E Ratio
2020 $1.37 Billion $5.48 Million -$32.55 Million 249.57x N/A
2021 $1.48 Billion $12.41 Million -$39.41 Million 119.60x N/A
2022 $947.85 Million $17.65 Million -$41.03 Million 53.69x N/A
2023 $1.08 Billion $25.38 Million -$43.27 Million 42.55x N/A
2024 $427.62 Million $43.26 Million -$45.31 Million 9.89x N/A
2025 $377.90 Million $559.00K -$88.61 Million 676.02x N/A

Competitor Companies of SLN by Market Capitalization

Companies near Silence Therapeutics PLC in the global market cap rankings as of November 1, 2026. Also see SLN total assets for a full breakdown of the balance sheet.

Key companies related to Silence Therapeutics PLC by market ranking:

  • Vertex Pharmaceuticals Inc (NASDAQ:VRTX): Ranked #182 globally with a market cap of $130.90 Billion USD.
  • Regeneron Pharmaceuticals Inc (NASDAQ:REGN): Ranked #371 globally with a market cap of $76.14 Billion USD.
  • CSL Ltd (AU:CSL): Ranked #412 globally with a market cap of $68.91 Billion USD ( AU$97.38 Billion AUD).
  • Moderna Inc (NASDAQ:MRNA): Ranked #495 globally with a market cap of $54.14 Billion USD.
Market capitalization comparison (in billions USD)
Rank Company Symbol Market Cap Price
#182 Vertex Pharmaceuticals Inc NASDAQ:VRTX $130.90 Billion $558.88
#371 Regeneron Pharmaceuticals Inc NASDAQ:REGN $76.14 Billion $927.89
#412 CSL Ltd AU:CSL $68.91 Billion AU$200.73
#495 Moderna Inc NASDAQ:MRNA $54.14 Billion $221.72

Market Capitalization of Silence Therapeutics PLC (2020–2026)

Market capitalization of Silence Therapeutics PLC from 2020 to today. Between 2020 and today, Silence Therapeutics PLC's market cap moved from $1.37 Billion to $ 1.23 Billion, with a yearly change of 0.21%.

Year Market Cap Change (%)
2026 $1.23 Billion +224.84%
2025 $377.90 Million -11.63%
2024 $427.62 Million -60.39%
2023 $1.08 Billion +13.90%
2022 $947.85 Million -36.17%
2021 $1.48 Billion +8.59%
2020 $1.37 Billion --

End of Day Market Cap According to Different Sources

On Oct 31st, 2026 the market cap of Silence Therapeutics PLC was reported to be:

Source Market Cap
Yahoo Finance $842.19 Million USD
MoneyControl $842.19 Million USD
MarketWatch $842.19 Million USD
marketcap.company $842.19 Million USD
Reuters $842.19 Million USD

Market cap values may vary slightly between sources due to differences in calculation methods, timing, and data refresh rates.

About Silence Therapeutics PLC

NASDAQ:SLN USA Biotechnology
Market Cap
$1.23 Billion
Market Cap Rank
#9277 Global
#2631 in USA
Share Price
$19.75
Change (1 day)
-0.25%
52-Week Range
$4.30 - $19.80
All Time High
$28.35
About

Silence Therapeutics plc, a biotechnology company, engages in the discovery and development of novel molecules incorporating short interfering ribonucleic acid (siRNA) to inhibit the expression of specific target genes in hematology, cardiovascular, and rare diseases. The company develops Divesiran (SLN124), which is in Phase 2 development for polycythemia vera, and SLN548 for complement-mediated… Read more