NASDAQ Biotechnology Index (NBI) Companies by Market Cap
The NASDAQ Biotechnology Index (NBI) tracks 263 constituent companies with a combined market cap of $1.74 Trillion, covering the largest publicly traded companies in USA. This ranking lists all NBI index holdings ordered by market capitalization — from the largest index heavyweights to smaller constituents. Updated daily with live market data.
Total Market Cap (USD)
$1.74 Trillion
Constituent Companies
263
Index Country
USA
| Rank | Company | Weight (%) | Market Cap (USD) | Sector | Industry | Price | 24h Change |
|---|---|---|---|---|---|---|---|
| 51 |
Immunovant Inc
NASDAQ:IMVT |
% | $5.91 Billion | Healthcare | Biotechnology | $38.70 | -2.54% |
| 52 |
Cogent Biosciences Inc
NASDAQ:COGT |
% | $5.86 Billion | Healthcare | Biotechnology | $37.46 | -3.63% |
| 53 |
Rhythm Pharmaceuticals Inc
NASDAQ:RYTM |
% | $5.84 Billion | Healthcare | Biotechnology | $107.49 | -0.84% |
| 54 |
CG Oncology, Inc. Common stock
NASDAQ:CGON |
% | $5.79 Billion | Healthcare | Biotechnology | $72.50 | -3.64% |
| 55 |
Erasca Inc
NASDAQ:ERAS |
% | $5.57 Billion | Healthcare | Biotechnology | $17.90 | -3.40% |
| 56 |
Protagonist Therapeutics Inc
NASDAQ:PTGX |
% | $5.09 Billion | Healthcare | Biotechnology | $129.89 | -1.16% |
| 57 |
Crispr Therapeutics AG
NASDAQ:CRSP |
% | $4.88 Billion | Healthcare | Biotechnology | $50.63 | -5.10% |
| 58 |
Legend Biotech Corp
NASDAQ:LEGN |
% | $4.78 Billion | Healthcare | Biotechnology | $25.75 | -4.91% |
| 59 |
Scholar Rock Holding Corp
NASDAQ:SRRK |
% | $4.69 Billion | Healthcare | Biotechnology | $54.70 | -3.54% |
| 60 |
Amicus Therapeutics Inc
NASDAQ:FOLD |
% | $4.55 Billion | Healthcare | Biotechnology | $14.49 | +0.00% |
| 61 |
Akero Therapeutics Inc
NASDAQ:AKRO |
% | $4.50 Billion | Healthcare | Biotechnology | $54.65 | +0.00% |
| 62 |
Twist Bioscience Corp
NASDAQ:TWST |
% | $4.31 Billion | Healthcare | Diagnostics & Research | $90.35 | -0.32% |
| 63 |
Travere Therapeutics Inc
NASDAQ:TVTX |
% | $3.96 Billion | Healthcare | Biotechnology | $56.29 | -0.53% |
| 64 |
Crinetics Pharmaceuticals Inc
NASDAQ:CRNX |
% | $3.95 Billion | Healthcare | Biotechnology | $83.67 | +0.11% |
| 65 |
Indivior PLC Ordinary Shares
NASDAQ:INDV |
% | $3.91 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $40.21 | -0.72% |
| 66 |
Dyne Therapeutics Inc
NASDAQ:DYN |
% | $3.91 Billion | Healthcare | Biotechnology | $23.64 | +0.94% |
| 67 |
NewAmsterdam Pharma Company N.V. Ordinary Shares
NASDAQ:NAMS |
% | $3.77 Billion | Healthcare | Biotechnology | $33.28 | -5.62% |
| 68 |
Structure Therapeutics Inc. American Depositary Shares
NASDAQ:GPCR |
% | $3.67 Billion | Healthcare | Biotechnology | $51.64 | -3.22% |
| 69 |
ACADIA Pharmaceuticals Inc
NASDAQ:ACAD |
% | $3.66 Billion | Healthcare | Biotechnology | $25.50 | -2.75% |
| 70 |
Edgewise Therapeutics Inc
NASDAQ:EWTX |
% | $3.66 Billion | Healthcare | Biotechnology | $41.27 | -9.12% |
| 71 |
Amneal Pharmaceuticals, Inc. Class A Common Stock
NYSE:AMRX |
% | $3.57 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $12.18 | +2.01% |
| 72 |
SpringWorks Therapeutics Inc
NASDAQ:SWTX |
% | $3.54 Billion | Healthcare | Biotechnology | $46.99 | +0.00% |
| 73 |
Tango Therapeutics Inc
NASDAQ:TNGX |
% | $3.39 Billion | Healthcare | Biotechnology | $28.36 | -8.69% |
| 74 |
Denali Therapeutics Inc
NASDAQ:DNLI |
% | $3.30 Billion | Healthcare | Biotechnology | $26.48 | +3.12% |
| 75 |
Xenon Pharmaceuticals Inc
NASDAQ:XENE |
% | $3.24 Billion | Healthcare | Biotechnology | $67.72 | -1.74% |
| 76 |
Beam Therapeutics Inc
NASDAQ:BEAM |
% | $3.19 Billion | Healthcare | Biotechnology | $31.00 | -5.14% |
| 77 |
Alumis Inc
NASDAQ:ALMS |
% | $3.01 Billion | Healthcare | Biotechnology | $28.10 | -0.74% |
| 78 |
Relay Therapeutics Inc
NASDAQ:RLAY |
% | $2.95 Billion | Healthcare | Biotechnology | $18.73 | -6.37% |
| 79 |
Veracyte Inc
NASDAQ:VCYT |
% | $2.83 Billion | Healthcare | Diagnostics & Research | $57.48 | +0.90% |
| 80 |
Kiniksa Pharmaceuticals Ltd
NASDAQ:KNSA |
% | $2.82 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $60.94 | -3.94% |
| 81 |
Supernus Pharmaceuticals Inc
NASDAQ:SUPN |
% | $2.75 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $47.35 | -2.29% |
| 82 |
Ligand Pharmaceuticals Incorporated
NASDAQ:LGND |
% | $2.69 Billion | Healthcare | Biotechnology | $309.25 | -2.21% |
| 83 |
Arcutis Biotherapeutics Inc
NASDAQ:ARQT |
% | $2.65 Billion | Healthcare | Biotechnology | $27.12 | -2.24% |
| 84 |
Disc Medicine Inc.
NASDAQ:IRON |
% | $2.61 Billion | Healthcare | Biotechnology | $75.98 | -0.80% |
| 85 |
Vera Therapeutics Inc
NASDAQ:VERA |
% | $2.60 Billion | Healthcare | Biotechnology | $41.50 | -1.19% |
| 86 |
GRAIL, LLC
NASDAQ:GRAL |
% | $2.58 Billion | Healthcare | Diagnostics & Research | $71.80 | -0.28% |
| 87 |
Ultragenyx
NASDAQ:RARE |
% | $2.57 Billion | Healthcare | Biotechnology | $33.22 | -1.77% |
| 88 |
Tarsus Pharmaceuticals Inc
NASDAQ:TARS |
% | $2.55 Billion | Healthcare | Biotechnology | $59.31 | +2.01% |
| 89 |
Ideaya Biosciences Inc
NASDAQ:IDYA |
% | $2.47 Billion | Healthcare | Biotechnology | $36.15 | -2.27% |
| 90 |
Enliven Therapeutics Inc.
NASDAQ:ELVN |
% | $2.46 Billion | Healthcare | Biotechnology | $50.87 | -0.43% |
| 91 |
Adaptive Biotechnologies Corp
NASDAQ:ADPT |
% | $2.43 Billion | Healthcare | Biotechnology | $21.02 | -0.19% |
| 92 |
10X Genomics Inc
NASDAQ:TXG |
% | $2.35 Billion | Healthcare | Health Information Services | $41.77 | -2.25% |
| 93 |
Trevi Therapeutics Inc
NASDAQ:TRVI |
% | $2.35 Billion | Healthcare | Biotechnology | $16.52 | -7.40% |
| 94 |
Mineralys Therapeutics, Inc. Common Stock
NASDAQ:MLYS |
% | $2.28 Billion | Healthcare | Biotechnology | $27.59 | -2.78% |
| 95 |
89bio Inc
NASDAQ:ETNB |
% | $2.20 Billion | Healthcare | Biotechnology | $14.84 | +0.00% |
| 96 |
Zai Lab Ltd
NASDAQ:ZLAB |
% | $2.20 Billion | Healthcare | Biotechnology | $19.62 | -4.25% |
| 97 |
BioCryst Pharmaceuticals Inc
NASDAQ:BCRX |
% | $2.18 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $9.91 | -5.17% |
| 98 |
Ocular Therapeutix Inc
NASDAQ:OCUL |
% | $2.16 Billion | Healthcare | Biotechnology | $9.88 | -3.14% |
| 99 |
Avadel Pharmaceuticals PLC
NASDAQ:AVDL |
% | $2.12 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $21.64 | +0.05% |
| 100 |
Aurinia Pharmaceuticals Inc
NASDAQ:AUPH |
% | $2.05 Billion | Healthcare | Biotechnology | $16.03 | +1.58% |
Complete list of all companies in the NBI index ranked by market capitalization. Track index constituent performance and market values. View all indices