NASDAQ Biotechnology Index (NBI) Companies by Market Cap
The NASDAQ Biotechnology Index (NBI) tracks 263 constituent companies with a combined market cap of $1.67 Trillion, covering the largest publicly traded companies in USA. This ranking lists all NBI index holdings ordered by market capitalization — from the largest index heavyweights to smaller constituents. Updated daily with live market data.
Total Market Cap (USD)
$1.67 Trillion
Constituent Companies
263
Index Country
USA
| Rank | Company | Weight (%) | Market Cap (USD) | Sector | Industry | Price | 24h Change |
|---|---|---|---|---|---|---|---|
| 51 |
Apellis Pharmaceuticals Inc
NASDAQ:APLS |
% | $5.20 Billion | Healthcare | Biotechnology | $40.96 | +0.02% |
| 52 |
Protagonist Therapeutics Inc
NASDAQ:PTGX |
% | $5.09 Billion | Healthcare | Biotechnology | $98.37 | -0.61% |
| 53 |
Crispr Therapeutics AG
NASDAQ:CRSP |
% | $4.96 Billion | Healthcare | Biotechnology | $51.63 | -1.36% |
| 54 |
Apogee Therapeutics, Inc. Common Stock
NASDAQ:APGE |
% | $4.93 Billion | Healthcare | Biotechnology | $80.75 | -2.58% |
| 55 |
Scholar Rock Holding Corp
NASDAQ:SRRK |
% | $4.69 Billion | Healthcare | Biotechnology | $46.37 | -0.51% |
| 56 |
Alkermes Plc
NASDAQ:ALKS |
% | $4.62 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $33.38 | -0.98% |
| 57 |
Amicus Therapeutics Inc
NASDAQ:FOLD |
% | $4.54 Billion | Healthcare | Biotechnology | $14.49 | +0.00% |
| 58 |
Akero Therapeutics Inc
NASDAQ:AKRO |
% | $4.50 Billion | Healthcare | Biotechnology | $54.65 | +0.00% |
| 59 |
Terns Pharmaceuticals Inc
NASDAQ:TERN |
% | $4.11 Billion | Healthcare | Biotechnology | $52.93 | +0.00% |
| 60 |
Crinetics Pharmaceuticals Inc
NASDAQ:CRNX |
% | $4.09 Billion | Healthcare | Biotechnology | $39.02 | +0.62% |
| 61 |
Arcellx Inc
NASDAQ:ACLX |
% | $4.04 Billion | Healthcare | Biotechnology | $115.07 | +0.00% |
| 62 |
Indivior PLC Ordinary Shares
NASDAQ:INDV |
% | $3.91 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $37.66 | +2.39% |
| 63 |
ACADIA Pharmaceuticals Inc
NASDAQ:ACAD |
% | $3.74 Billion | Healthcare | Biotechnology | $21.95 | -2.23% |
| 64 |
Ligand Pharmaceuticals Incorporated
NASDAQ:LGND |
% | $3.62 Billion | Healthcare | Biotechnology | $227.44 | -0.88% |
| 65 |
Amneal Pharmaceuticals, Inc. Class A Common Stock
NYSE:AMRX |
% | $3.57 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $12.18 | +2.01% |
| 66 |
SpringWorks Therapeutics Inc
NASDAQ:SWTX |
% | $3.54 Billion | Healthcare | Biotechnology | $46.99 | +0.02% |
| 67 |
Legend Biotech Corp
NASDAQ:LEGN |
% | $3.25 Billion | Healthcare | Biotechnology | $23.59 | +0.30% |
| 68 |
Xenon Pharmaceuticals Inc
NASDAQ:XENE |
% | $3.24 Billion | Healthcare | Biotechnology | $56.13 | +0.16% |
| 69 |
Edgewise Therapeutics Inc
NASDAQ:EWTX |
% | $3.24 Billion | Healthcare | Biotechnology | $30.61 | -1.13% |
| 70 |
NewAmsterdam Pharma Company N.V. Ordinary Shares
NASDAQ:NAMS |
% | $3.22 Billion | Healthcare | Biotechnology | $28.43 | -0.46% |
| 71 |
Erasca Inc
NASDAQ:ERAS |
% | $3.12 Billion | Healthcare | Biotechnology | $10.03 | -5.82% |
| 72 |
Twist Bioscience Corp
NASDAQ:TWST |
% | $3.01 Billion | Healthcare | Diagnostics & Research | $60.40 | +3.34% |
| 73 |
Structure Therapeutics Inc. American Depositary Shares
NASDAQ:GPCR |
% | $2.99 Billion | Healthcare | Biotechnology | $42.21 | +1.83% |
| 74 |
Alumis Inc
NASDAQ:ALMS |
% | $2.92 Billion | Healthcare | Biotechnology | $25.18 | +1.98% |
| 75 |
Travere Therapeutics Inc
NASDAQ:TVTX |
% | $2.90 Billion | Healthcare | Biotechnology | $44.12 | +4.75% |
| 76 |
Arcutis Biotherapeutics Inc
NASDAQ:ARQT |
% | $2.90 Billion | Healthcare | Biotechnology | $23.35 | +0.56% |
| 77 |
Dyne Therapeutics Inc
NASDAQ:DYN |
% | $2.87 Billion | Healthcare | Biotechnology | $17.39 | -0.91% |
| 78 |
Denali Therapeutics Inc
NASDAQ:DNLI |
% | $2.86 Billion | Healthcare | Biotechnology | $18.30 | -2.24% |
| 79 |
Spyre Therapeutics Inc.
NASDAQ:SYRE |
% | $2.84 Billion | Healthcare | Biotechnology | $69.42 | -6.76% |
| 80 |
Supernus Pharmaceuticals Inc
NASDAQ:SUPN |
% | $2.74 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $47.85 | -0.31% |
| 81 |
Tarsus Pharmaceuticals Inc
NASDAQ:TARS |
% | $2.69 Billion | Healthcare | Biotechnology | $63.62 | +0.02% |
| 82 |
Beam Therapeutics Inc
NASDAQ:BEAM |
% | $2.66 Billion | Healthcare | Biotechnology | $30.70 | +1.22% |
| 83 |
Veracyte Inc
NASDAQ:VCYT |
% | $2.62 Billion | Healthcare | Diagnostics & Research | $33.09 | +0.52% |
| 84 |
ADMA Biologics Inc
NASDAQ:ADMA |
% | $2.51 Billion | Healthcare | Biotechnology | $10.52 | +2.63% |
| 85 |
Vera Therapeutics Inc
NASDAQ:VERA |
% | $2.50 Billion | Healthcare | Biotechnology | $35.20 | -1.15% |
| 86 |
Kiniksa Pharmaceuticals Ltd
NASDAQ:KNSA |
% | $2.50 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $55.27 | +2.77% |
| 87 |
Ideaya Biosciences Inc
NASDAQ:IDYA |
% | $2.47 Billion | Healthcare | Biotechnology | $28.19 | -3.13% |
| 88 |
10X Genomics Inc
NASDAQ:TXG |
% | $2.35 Billion | Healthcare | Health Information Services | $22.43 | +1.72% |
| 89 |
Zai Lab Ltd
NASDAQ:ZLAB |
% | $2.24 Billion | Healthcare | Biotechnology | $21.54 | -0.46% |
| 90 |
89bio Inc
NASDAQ:ETNB |
% | $2.20 Billion | Healthcare | Biotechnology | $14.84 | +0.00% |
| 91 |
Adaptive Biotechnologies Corp
NASDAQ:ADPT |
% | $2.19 Billion | Healthcare | Biotechnology | $14.27 | +1.21% |
| 92 |
Mineralys Therapeutics, Inc. Common Stock
NASDAQ:MLYS |
% | $2.16 Billion | Healthcare | Biotechnology | $29.26 | +9.79% |
| 93 |
Avadel Pharmaceuticals PLC
NASDAQ:AVDL |
% | $2.12 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $21.64 | +0.05% |
| 94 |
Disc Medicine Inc.
NASDAQ:IRON |
% | $2.11 Billion | Healthcare | Biotechnology | $66.91 | +1.46% |
| 95 |
Aurinia Pharmaceuticals Inc
NASDAQ:AUPH |
% | $2.04 Billion | Healthcare | Biotechnology | $15.35 | -0.23% |
| 96 |
Ocular Therapeutix Inc
NASDAQ:OCUL |
% | $2.02 Billion | Healthcare | Biotechnology | $9.43 | +0.64% |
| 97 |
Ultragenyx
NASDAQ:RARE |
% | $1.98 Billion | Healthcare | Biotechnology | $24.77 | +0.32% |
| 98 |
AnaptysBio Inc
NASDAQ:ANAB |
% | $1.92 Billion | Healthcare | Biotechnology | $66.76 | +1.57% |
| 99 |
Galapagos NV ADR
NASDAQ:GLPG |
% | $1.89 Billion | Healthcare | Biotechnology | $28.68 | -1.58% |
| 100 |
BioCryst Pharmaceuticals Inc
NASDAQ:BCRX |
% | $1.87 Billion | Healthcare | Drug Manufacturers - Specialty & Generic | $9.19 | +0.33% |
Complete list of all companies in the NBI index ranked by market capitalization. Track index constituent performance and market values. View all indices