Spyre Therapeutics Inc. (SYRE) - Cash Flow Conversion Efficiency

Latest as of March 2026: -0.086x

Based on the latest financial reports, Spyre Therapeutics Inc. (SYRE) has a cash flow conversion efficiency ratio of -0.086x as of March 2026. Cash flow conversion efficiency measures how effectively a company's net assets (equity) generate operating cash flow. It is calculated by dividing operating cash flow ($-57.54 Million) by net assets ($670.81 Million). A higher ratio indicates that the company is more efficient at using its equity to generate cash flow from its core operations. See debt-free asset ratio of Spyre Therapeutics Inc. to measure how much of total assets are equity-financed.

Spyre Therapeutics Inc. - Cash Flow Conversion Efficiency Trend (2014–2025)

This chart illustrates how Spyre Therapeutics Inc.'s cash flow conversion efficiency has evolved over time, based on yearly financial data. Check SYRE capex plus investments ratio to assess the company's total reinvestment commitment from operating cash flow.

Spyre Therapeutics Inc. Competitors by Cash Flow Conversion Efficiency

The table below lists competitors of Spyre Therapeutics Inc. ranked by their cash flow conversion efficiency.

Company Cash Flow Conversion Efficiency
GUOTAI JUNAN SEC. H YC1
F:153A
0.155x
D-Wave Quantum Inc.
NYSE:QBTS
-0.040x
Unicaja Banco SA
MC:UNI
0.006x
Avanza Bank Holding AB (publ)
ST:AZA
1.029x
KION GROUP AG ADRS/1/4
F:KGX1
0.037x
The Hanover Insurance Group Inc
NYSE:THG
0.033x
Ringkjoebing Landbobank A/S
CO:RILBA
0.002x
Dosilicon Co Ltd
SHG:688110
-0.029x

Annual Cash Flow Conversion Efficiency for Spyre Therapeutics Inc. (2014–2025)

The table below shows the annual cash flow conversion efficiency of Spyre Therapeutics Inc. from 2014 to 2025. For the full company profile with market capitalisation and key ratios, see SYRE stock market capitalisation.

Year Net Assets Operating Cash Flow Cash Flow Conversion Efficiency Change
2025-12-31 $715.24 Million $-169.25 Million -0.237x +22.16%
2024-12-31 $517.80 Million $-157.41 Million -0.304x +44.01%
2023-12-31 $184.02 Million $-99.91 Million -0.543x +65.92%
2022-12-31 $50.30 Million $-80.14 Million -1.593x -148.96%
2021-12-31 $83.94 Million $-53.72 Million -0.640x -18.09%
2020-12-31 $139.83 Million $-75.78 Million -0.542x +50.44%
2019-12-31 $60.08 Million $-65.69 Million -1.093x -129.01%
2018-12-31 $67.43 Million $-32.19 Million -0.477x +2.36%
2017-12-31 $50.34 Million $-24.61 Million -0.489x -63.43%
2016-12-31 $62.97 Million $-18.84 Million -0.299x +1.63%
2015-12-31 $36.10 Million $-10.98 Million -0.304x +92.24%
2014-12-31 $1.87 Million $-7.33 Million -3.918x --

About Spyre Therapeutics Inc.

NASDAQ:SYRE USA Biotechnology
Market Cap
$8.54 Billion
Market Cap Rank
#2947 Global
#1048 in USA
Share Price
$98.33
Change (1 day)
-3.12%
52-Week Range
$14.82 - $102.70
All Time High
$299.75
About

Spyre Therapeutics, Inc., a clinical stage biotechnology company, focuses on developing therapeutics for patients living with inflammatory bowel disease (IBD) and rheumatic diseases. The company develops SPY001, a humanized monoclonal immunoglobulin G1 antibody that is in phase-2 clinical stage designed to bind selectively to the a4ß7 integrin being developed for the treatment of IBD (ulcerative … Read more