Spyre Therapeutics Inc. Cash Flow-to-Debt Ratio

Latest as of June 2026: -0.97x

Spyre Therapeutics Inc. cash flow-to-debt ratio. Spyre Therapeutics Inc. (SYRE) has a Cash Flow-to-Debt Ratio of -0.97x as of June 2026, meaning its operating cash flow of $-69.88 Million could theoretically repay -1% of its total liabilities ($71.86 Million) in one year. See Spyre Therapeutics Inc. (SYRE) flexibility index to measure the company's free cash flow as a share of total liabilities.

CF-to-Debt Ratio

-0.97x
Operating CF / Total Liabilities

Operating Cash Flow

$-69.88 Million
USD

Total Liabilities

$71.86 Million
USD

Data as of

Jun 2026
Most recent filing

Cash Flow-to-Debt Ratio of Spyre Therapeutics Inc. (2014–2025)

Cash flow-to-debt ratio of Spyre Therapeutics Inc. from 2014 to 2025. Historical debt coverage capacity for Spyre Therapeutics Inc. across 12 annual periods. Check SYRE cash reinvestment to operating cash ratio to assess the company's total reinvestment commitment from operating cash flow.

Spyre Therapeutics Inc. Cash Flow-to-Debt Ratio by Year (2014–2025)

Spyre Therapeutics Inc. cash flow-to-debt ratio by year from 2014 to 2025. Year-by-year debt coverage analysis for Spyre Therapeutics Inc.. For the full cash flow conversion analysis, see Spyre Therapeutics Inc. (SYRE) cash flow conversion.

Year CF-to-Debt Ratio Operating CF (USD) Total Liabilities YoY Change
2025 -2.71x $-169.25 Million $62.55 Million ▼ -55.9%
2024 -1.74x $-157.41 Million $90.68 Million ▼ -174.2%
2023 -0.63x $-99.91 Million $157.84 Million ▲ +83.5%
2022 -3.85x $-80.14 Million $20.84 Million ▼ -86.0%
2021 -2.07x $-53.72 Million $25.98 Million ▲ +40.6%
2020 -3.48x $-75.78 Million $21.79 Million ▼ -22.3%
2019 -2.84x $-65.69 Million $23.10 Million ▲ +8.9%
2018 -3.12x $-32.19 Million $10.31 Million ▲ +27.2%
2017 -4.29x $-24.61 Million $5.74 Million ▲ +6.7%
2016 -4.60x $-18.84 Million $4.10 Million ▼ -6.8%
2015 -4.31x $-10.98 Million $2.55 Million ▲ +37.9%
2014 -6.93x $-7.33 Million $1.06 Million —
Cash Flow-to-Debt Ratio = Operating Cash Flow / Total Liabilities. Higher is better for debt service capacity.