Spyre Therapeutics Inc. (SYRE) — Cash Flow-to-Debt Ratio

Latest as of March 2026: -0.62x

Spyre Therapeutics Inc. (SYRE) has a Cash Flow-to-Debt Ratio of -0.62x as of March 2026, meaning its operating cash flow of $-57.54 Million could theoretically repay -1% of its total liabilities ($93.14 Million) in one year. Check Spyre Therapeutics Inc. (SYRE) total reinvestment rate to assess the company's total reinvestment commitment from operating cash flow.

CF-to-Debt Ratio

-0.62x
Operating CF / Total Liabilities

Operating Cash Flow

$-57.54 Million
USD

Total Liabilities

$93.14 Million
USD

Data as of

Mar 2026
Most recent filing

Spyre Therapeutics Inc. Cash Flow-to-Debt Ratio (2014–2025)

Historical debt coverage capacity for Spyre Therapeutics Inc. across 12 annual periods. Also explore SYRE asset base for the complete picture of this company's asset base.

Annual Cash Flow-to-Debt Ratio for Spyre Therapeutics Inc. (2014–2025)

Year-by-year debt coverage analysis for Spyre Therapeutics Inc.. For market capitalisation and broader financial context, see Spyre Therapeutics Inc. market capitalisation.

Year CF-to-Debt Ratio Operating CF (USD) Total Liabilities YoY Change
2025 -2.71x $-169.25 Million $62.55 Million ▼ -55.9%
2024 -1.74x $-157.41 Million $90.68 Million ▼ -174.2%
2023 -0.63x $-99.91 Million $157.84 Million ▲ +83.5%
2022 -3.85x $-80.14 Million $20.84 Million ▼ -86.0%
2021 -2.07x $-53.72 Million $25.98 Million ▲ +40.6%
2020 -3.48x $-75.78 Million $21.79 Million ▼ -22.3%
2019 -2.84x $-65.69 Million $23.10 Million ▲ +8.9%
2018 -3.12x $-32.19 Million $10.31 Million ▲ +27.2%
2017 -4.29x $-24.61 Million $5.74 Million ▲ +6.7%
2016 -4.60x $-18.84 Million $4.10 Million ▼ -6.8%
2015 -4.31x $-10.98 Million $2.55 Million ▲ +37.9%
2014 -6.93x $-7.33 Million $1.06 Million
Cash Flow-to-Debt Ratio = Operating Cash Flow / Total Liabilities. Higher is better for debt service capacity.