Spyre Therapeutics Inc. (SYRE) — Defensive Interval Ratio

Latest as of June 2026: 5670 days

Spyre Therapeutics Inc. (SYRE) has a Defensive Interval Ratio of 5670 days as of June 2026. Defensive assets of $983.34 Million (cash $-, short-term investments $983.34 Million, receivables $-) cover 5670 days of daily cash needs of $173.43K/day.

Defensive Interval Ratio

5670 days
Days of operational coverage

Defensive Assets

$983.34 Million
Cash + ST Investments + Receivables

Daily Cash Need

$173.43K
Current Liabilities ÷ 365

Current Liabilities

$63.30 Million
USD

Spyre Therapeutics Inc. Defensive Interval Ratio (2015–2025)

This chart shows how Spyre Therapeutics Inc.'s Defensive Interval Ratio has evolved across 11 annual periods from 2015 to 2025. As of June 2026, the ratio stands at 5670 days, meaning defensive assets of $983.34 Million can fund 5670 days of operations without new revenue. For the complete balance sheet picture, see SYRE asset base.

Annual Defensive Interval Ratio for Spyre Therapeutics Inc. (2015–2025)

The table below presents the year-by-year Defensive Interval Ratio for Spyre Therapeutics Inc. from 2015 to 2025, covering 11 annual filings. Each row shows defensive assets, daily cash need, the DIR in days, and the change in days compared to the prior year. See Spyre Therapeutics Inc. (SYRE) liquidity to equity ratio to evaluate short-term liquidity relative to the company's equity base.

Year DIR (days) Defensive Assets (USD) Daily Cash Need Cash ST Investments Change (days)
2025 4172 days $670.81 Million $160.78K/day $- $670.81 Million ▲ +704 days
2024 3468 days $513.66 Million $148.11K/day $- $513.66 Million ▲ +1752 days
2023 1716 days $150.38 Million $87.61K/day $- $150.38 Million ▲ +1188 days
2022 529 days $21.22 Million $40.15K/day $- $20.85 Million ▼ -899 days
2021 1428 days $78.80 Million $55.19K/day $- $77.99 Million ▲ +181 days
2020 1247 days $56.18 Million $45.05K/day $- $56.18 Million ▲ +199 days
2019 1048 days $52.70 Million $50.30K/day $- $52.70 Million ▼ -819 days
2018 1866 days $52.35 Million $28.05K/day $- $52.05 Million ▼ -764 days
2017 2630 days $40.56 Million $15.42K/day $- $37.48 Million ▲ +1068 days
2016 1562 days $16.97 Million $10.86K/day $- $15.75 Million ▲ +771 days
2015 791 days $5.46 Million $6.91K/day $- $3.77 Million
DIR = (Cash + Short-term Investments + Net Receivables) / (Daily Cash Expenses)