Spyre Therapeutics Inc. (SYRE) — Defensive Interval Ratio
Spyre Therapeutics Inc. (SYRE) has a Defensive Interval Ratio of 2781 days as of March 2026. Defensive assets of $648.88 Million (cash $-, short-term investments $644.28 Million, receivables $4.60 Million) cover 2781 days of daily cash needs of $233.32K/day. See Spyre Therapeutics Inc. working capital to net assets to evaluate short-term liquidity relative to the company's equity base.
Defensive Interval Ratio
Defensive Assets
Daily Cash Need
Current Liabilities
Spyre Therapeutics Inc. Defensive Interval Ratio (2015–2025)
This chart shows how Spyre Therapeutics Inc.'s Defensive Interval Ratio has evolved across 11 annual periods from 2015 to 2025. As of March 2026, the ratio stands at 2781 days, meaning defensive assets of $648.88 Million can fund 2781 days of operations without new revenue. See Spyre Therapeutics Inc. balance sheet independence to measure how much of total assets are equity-financed.
Annual Defensive Interval Ratio for Spyre Therapeutics Inc. (2015–2025)
The table below presents the year-by-year Defensive Interval Ratio for Spyre Therapeutics Inc. from 2015 to 2025, covering 11 annual filings. Each row shows defensive assets, daily cash need, the DIR in days, and the change in days compared to the prior year. For live market cap and the full company financial profile, see SYRE market cap overview.
| Year | DIR (days) | Defensive Assets (USD) | Daily Cash Need | Cash | ST Investments | Change (days) |
|---|---|---|---|---|---|---|
| 2025 | 4172 days | $670.81 Million | $160.78K/day | $- | $670.81 Million | ▲ +704 days |
| 2024 | 3468 days | $513.66 Million | $148.11K/day | $- | $513.66 Million | ▲ +1752 days |
| 2023 | 1716 days | $150.38 Million | $87.61K/day | $- | $150.38 Million | ▲ +1188 days |
| 2022 | 529 days | $21.22 Million | $40.15K/day | $- | $20.85 Million | ▼ -899 days |
| 2021 | 1428 days | $78.80 Million | $55.19K/day | $- | $77.99 Million | ▲ +181 days |
| 2020 | 1247 days | $56.18 Million | $45.05K/day | $- | $56.18 Million | ▲ +199 days |
| 2019 | 1048 days | $52.70 Million | $50.30K/day | $- | $52.70 Million | ▼ -819 days |
| 2018 | 1866 days | $52.35 Million | $28.05K/day | $- | $52.05 Million | ▼ -764 days |
| 2017 | 2630 days | $40.56 Million | $15.42K/day | $- | $37.48 Million | ▲ +1068 days |
| 2016 | 1562 days | $16.97 Million | $10.86K/day | $- | $15.75 Million | ▲ +771 days |
| 2015 | 791 days | $5.46 Million | $6.91K/day | $- | $3.77 Million | — |