Spyre Therapeutics Inc. (SYRE) — Financial Flexibility Index

Latest as of March 2026: -0.62x

Spyre Therapeutics Inc. (SYRE) has a Financial Flexibility Index of -0.62x as of March 2026. Free cash flow of $-57.54 Million (operating CF $-57.54 Million minus capex $0.00) represents -1% of total liabilities ($93.14 Million). Check SYRE financial resilience to evaluate the company's liquid asset resilience ratio.

Financial Flexibility Index

-0.62x
Free Cash Flow / Total Liabilities

Free Cash Flow

$-57.54 Million
Operating CF − Capex

Total Liabilities

$93.14 Million
USD

Capital Expenditures

$0.00
USD

Spyre Therapeutics Inc. Financial Flexibility Index (2014–2025)

Historical Financial Flexibility Index trend for Spyre Therapeutics Inc. across 12 annual periods. See SYRE working capital efficiency to evaluate short-term liquidity relative to the company's equity base.

Annual Financial Flexibility Index for Spyre Therapeutics Inc. (2014–2025)

Year-by-year free cash flow to debt coverage for Spyre Therapeutics Inc.. For the full company profile including market capitalisation, see how much is Spyre Therapeutics Inc. worth.

Year Flexibility Index Free Cash Flow (USD) Operating CF Total Liabilities YoY Change
2025 -2.71x $-169.25 Million $-169.25 Million $62.55 Million ▼ -55.9%
2024 -1.74x $-157.41 Million $-157.41 Million $90.68 Million ▼ -174.2%
2023 -0.63x $-99.91 Million $-99.91 Million $157.84 Million ▲ +83.5%
2022 -3.84x $-80.11 Million $-80.14 Million $20.84 Million ▼ -88.0%
2021 -2.05x $-53.14 Million $-53.72 Million $25.98 Million ▲ +37.7%
2020 -3.28x $-71.50 Million $-75.78 Million $21.79 Million ▼ -18.1%
2019 -2.78x $-64.20 Million $-65.69 Million $23.10 Million ▲ +9.8%
2018 -3.08x $-31.77 Million $-32.19 Million $10.31 Million ▲ +26.3%
2017 -4.18x $-24.00 Million $-24.61 Million $5.74 Million ▲ +8.1%
2016 -4.55x $-18.63 Million $-18.84 Million $4.10 Million ▼ -7.6%
2015 -4.23x $-10.77 Million $-10.98 Million $2.55 Million ▲ +37.5%
2014 -6.76x $-7.15 Million $-7.33 Million $1.06 Million
Financial Flexibility Index = (Operating CF − Capex) / Total Liabilities = Free Cash Flow / Total Liabilities