Spyre Therapeutics Inc. (SYRE) — Financial Flexibility Index
Spyre Therapeutics Inc. (SYRE) has a Financial Flexibility Index of -0.97x as of June 2026. Free cash flow of $-69.88 Million (operating CF $-69.88 Million minus capex $0.00) represents -1% of total liabilities ($71.86 Million). Check SYRE capex plus investments ratio to assess the company's total reinvestment commitment from operating cash flow.
Financial Flexibility Index
Free Cash Flow
Total Liabilities
Capital Expenditures
Spyre Therapeutics Inc. Financial Flexibility Index (2014–2025)
Historical Financial Flexibility Index trend for Spyre Therapeutics Inc. across 12 annual periods. For the full cash flow conversion analysis, see SYRE cash generation efficiency.
Annual Financial Flexibility Index for Spyre Therapeutics Inc. (2014–2025)
Year-by-year free cash flow to debt coverage for Spyre Therapeutics Inc.. Explore how well can Spyre Therapeutics Inc. service its debt to assess how comfortably operating cash covers total debt obligations.
| Year | Flexibility Index | Free Cash Flow (USD) | Operating CF | Total Liabilities | YoY Change |
|---|---|---|---|---|---|
| 2025 | -2.71x | $-169.25 Million | $-169.25 Million | $62.55 Million | ▼ -55.9% |
| 2024 | -1.74x | $-157.41 Million | $-157.41 Million | $90.68 Million | ▼ -174.2% |
| 2023 | -0.63x | $-99.91 Million | $-99.91 Million | $157.84 Million | ▲ +83.5% |
| 2022 | -3.84x | $-80.11 Million | $-80.14 Million | $20.84 Million | ▼ -88.0% |
| 2021 | -2.05x | $-53.14 Million | $-53.72 Million | $25.98 Million | ▲ +37.7% |
| 2020 | -3.28x | $-71.50 Million | $-75.78 Million | $21.79 Million | ▼ -18.1% |
| 2019 | -2.78x | $-64.20 Million | $-65.69 Million | $23.10 Million | ▲ +9.8% |
| 2018 | -3.08x | $-31.77 Million | $-32.19 Million | $10.31 Million | ▲ +26.3% |
| 2017 | -4.18x | $-24.00 Million | $-24.61 Million | $5.74 Million | ▲ +8.1% |
| 2016 | -4.55x | $-18.63 Million | $-18.84 Million | $4.10 Million | ▼ -7.6% |
| 2015 | -4.23x | $-10.77 Million | $-10.98 Million | $2.55 Million | ▲ +37.5% |
| 2014 | -6.76x | $-7.15 Million | $-7.33 Million | $1.06 Million | — |